201686-63-7

Basic information

• Product Name: 6-[bis-(5-fluoro-2-methyl-benzoyl)-amino]-nicotinic acid ethyl ester
• CAS NO: 201686-63-7
• Molecular Weight: 438.431
• Mol File: 201686-63-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-[bis-(5-fluoro-2-methyl-benzoyl)-amino]-nicotinic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[bis-(5-fluoro-2-methyl-benzoyl)-amino]-nicotinic acid ethyl ester(201686-63-7)
• EPA Substance Registry System: 6-[bis-(5-fluoro-2-methyl-benzoyl)-amino]-nicotinic acid ethyl ester(201686-63-7)

Safety Data

• Hazardous Substances Data: 201686-63-7(Hazardous Substances Data)

Upstream product

• 39658-41-8 ethyl-6-amino-nicotinate 
• 21900-39-0 5-fluoro-2-methylbenzoyl chloride 

Downstream Products

• 180416-31-3 N-[5-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)-2-pyridinyl]-5-fluoro-2-methylbenzamide 
• 180340-68-5 6-[(5-fluoro-2-methylbenzoyl)amino]pyridine-3-carbonyl chloride 
• 180339-39-3 6-[(5-fluoro-2-methylbenzoyl)amino]pyridine-3-carboxylic acid 

Relevant articles and documents

5-Fluoro-2-methyl-N-[5-(5H-pyrrolo[2,1-c][1,4]benzodiazepine-10(11H)-yl carbonyl)-2-pyridinyl]benzamide (CL-385004) and analogs as orally active arginine vasopressin receptor antagonists

Synthesis and structure-activity relationships (SAR) of orally active arginine vasopressin (AVP) receptor antagonists are discussed. Potent and orally active AVP receptor antagonists are produced when ring A of VPA-985 (1) is replaced with a 3-pyridinyl unit (2b).