202740-27-0

Basic information

• Product Name: (S)-1-{[2-(4-nitrophenyl)ethyl]amino}-3-phenoxypropan-2-ol
• Synonyms: (S)-1-{[2-(4-nitrophenyl)ethyl]amino}-3-phenoxypropan-2-ol
• CAS NO: 202740-27-0
• Molecular Weight: 316.357
• Mol File: 202740-27-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (S)-1-{[2-(4-nitrophenyl)ethyl]amino}-3-phenoxypropan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-{[2-(4-nitrophenyl)ethyl]amino}-3-phenoxypropan-2-ol(202740-27-0)
• EPA Substance Registry System: (S)-1-{[2-(4-nitrophenyl)ethyl]amino}-3-phenoxypropan-2-ol(202740-27-0)

Safety Data

• Hazardous Substances Data: 202740-27-0(Hazardous Substances Data)

Upstream product

• 29968-78-3 2-(4-nitrophenyl)ethylamine monohydrochloride 
• 71031-03-3 (R)-phenyl glycidyl ether 

Downstream Products

• 202740-28-1 tert-butyl (S)-N-(2-hydroxy-3-phenoxy)propyl-N-[2-(4-nitrophenyl)ethyl]carbamate 
• 211103-25-2 tert-butyl (S)-N-(2-hydroxy-3-phenoxypropyl)-N-[2-(4-{[2-(2-phenylaminothiazol-4-yl)acetyl]amino}phenyl)ethyl]carbamate 
• 391901-77-2 (1 S)-2-[(tert-Butoxycarbonyl)(4-nitrophenethyl)amino]-1-(phenoxymethyl) ethyl tert-butyl carbonate 
• 159183-36-5 tert-butyl (S)-N-[2-(4-aminophenyl)ethyl]-N-(2-hydroxy-3-phenoxy)propylcarbamate 

Relevant articles and documents

Chemoselective and Kilogram-Scale Synthesis of Acetanilide β3-Adrenergic Receptor Agonist

We describe an alternative route for the synthesis of β3-adrenergic receptor agonist (S)-2-(2-phenylamino-1,3- thiazol-4-yl)-4′-{2-[(2-hydroxy-3-phenoxypropyl)amino]ethyl}acetanilide (1). The key intermediate (S)-1-{[2-(4-aminophenyl)ethyl]amin

Azolidines as beta-3 adrenergic receptor agonists

This invention provides compounds of Formula I having the structure wherein, A, X, Y, Z, W, R1, R2, R3, R4, R5, and R6 are as defined hereinbefore or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated with obesity or glucose intolerance), atherosclerosis, gastrointestinal disorders, neurogenetic inflammation, glaucoma, ocular hypertension and frequent urination; and are particularly useful in the treatment or inhibition of type II diabetes.