203180-28-3

Basic information

• Product Name: 4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-3-methyl-piperazin-1-yl)-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 203180-28-3
• Molecular Weight: 571.738
• Mol File: 203180-28-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-3-methyl-piperazin-1-yl)-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-3-methyl-piperazin-1-yl)-piperidine-1-carboxylic acid tert-butyl ester(203180-28-3)
• EPA Substance Registry System: 4-((R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-3-methyl-piperazin-1-yl)-piperidine-1-carboxylic acid tert-butyl ester(203180-28-3)

Safety Data

• Hazardous Substances Data: 203180-28-3(Hazardous Substances Data)

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 203180-27-2 (R)-1-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-2-methyl-piperazine 
• 5876-51-7 5-iodo-1,3-benzodioxole 
• 441772-07-2 (R)-1-[(S)-1-(4-Bromo-phenyl)-ethyl]-6-methyl-piperazine-2,5-dione 
• 441772-08-3 (R)-1-[(S)-1-(4-Bromo-phenyl)-ethyl]-2-methyl-piperazine 
• 182141-70-4 N-[(1S)-1-(4-bromophenyl)ethyl]-2,2,2-trifluoroacetamide 
• 27298-97-1 (S)-1-(4-bromophenyl)ethylamine 
• 2354-91-8 (S)-2,2,2-trifluoro-(α-methylbenzyl)acetamide 
• 442868-88-4 (R)-4-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-3-methyl-piperazine-1-carboxylic acid tert-butyl ester 
• 203180-24-9 Methanesulfonic acid (R)-1-[4-(benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl ester 
• 442868-87-3 1-[4-(benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethanone 
• 203180-21-6 1-[4-(benzo[1,3]dioxol-5-ylsulfanyl)-phenyl]-ethanone 
• 163765-44-4 (R)-tert-butyl 3-methylpiperazine-1-carboxylate 
• 403-42-9 1-(4-fluorophenyl)ethanone 

Downstream Products

• 203180-30-7 (R)-1-{(S)-1-[4-(Benzo[1,3]dioxole-5-sulfonyl)-phenyl]-ethyl}-2-methyl-4-piperidin-4-yl-piperazine 

Relevant articles and documents

Substituted 2-(R)-Methyl piperazines as muscarinic M2 selective ligands

A novel series of 2-(R)-methyl-substituted piperazines (e.g., 2) is described. They are potent M2 selective ligands that have > 100-fold selectivity versus the M1 receptor. In the rat microdialysis assay, compound 14 showed significantly enchanced levels of acetylcholine after oral administration.