20395-28-2 Usage
Description
5-Chloropentyl acetate is a Friedel-Crafts haloalkyl ester that is characterized by its clear colorless liquid appearance. It possesses antibacterial properties, making it a valuable compound in various applications.
Uses
Used in Pharmaceutical Industry:
5-Chloropentyl acetate is used as an active pharmaceutical ingredient for its antibacterial properties. It is particularly effective in combating various bacterial infections due to its ability to disrupt bacterial cell membranes and inhibit essential cellular processes.
Used in Chemical Synthesis:
In the field of chemical synthesis, 5-chloropentyl acetate serves as a versatile intermediate for the production of various organic compounds. Its reactivity as a haloalkyl ester allows for a range of synthetic transformations, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Material Science:
5-Chloropentyl acetate can be utilized in the development of novel materials with enhanced properties. Its incorporation into polymers and other materials can lead to improved mechanical strength, thermal stability, and resistance to degradation, making it a promising candidate for applications in the material science industry.
Used in Cosmetics and Personal Care:
In the cosmetics and personal care industry, 5-chloropentyl acetate can be employed as a preservative or additive to enhance the shelf life and efficacy of various products. Its antibacterial properties help to prevent the growth of harmful microorganisms, ensuring the safety and integrity of cosmetic and personal care products.
Used in Surface Disinfection:
5-Chloropentyl acetate can be applied in the formulation of surface disinfectants for use in healthcare, food processing, and other industries. Its ability to kill or inhibit the growth of bacteria on surfaces makes it an effective component in the development of cleaning and sanitizing products.
Synthesis Reference(s)
The Journal of Organic Chemistry, 48, p. 751, 1983 DOI: 10.1021/jo00153a031
Check Digit Verification of cas no
The CAS Registry Mumber 20395-28-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,3,9 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 20395-28:
(7*2)+(6*0)+(5*3)+(4*9)+(3*5)+(2*2)+(1*8)=92
92 % 10 = 2
So 20395-28-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H13ClO2/c1-7(9)10-6-4-2-3-5-8/h2-6H2,1H3
20395-28-2Relevant articles and documents
Synthesis of chloroesters by the cleavage of cyclic and acyclic ethers using La(NO3)3·6H2O as a mild and efficient catalyst under solvent-free conditions
Suresh,Suryakiran,Rajesh,Selvam, J. Jon Paul,Srinivasulu,Venkateswarlu
, p. 92 - 99 (2008)
A mild and an efficient synthesis of chloroesters is described by the reaction of cyclic and acyclic ethers with acid chlorides in the presence of a catalytic amount of La(NO3)3·6H2O under solvent-free conditions, affording the corresponding chloroesters in excellent yields. Copyright Taylor & Francis Group, LLC.
Synthesis of an azide-tethered 4H-furo[3,4-b]indole
Keavy, Daniel J.,Liu, Yanbing,Gribble, Gordon W.
, p. 368 - 375 (2020/02/13)
We describe the synthesis of a novel azide-tethered 4H-furo[3,4-b]indole as a putative intermediate for a projected route to the 2-acylindole class of indole alkaloids. O N3 Me N N N H N H H O
An efficient iron catalyzed regioselective acylative cleavage of ethers: Scope and mechanism
Bodduri, V.D. Vijaykumar,Choi, Kyung-Min,Vaidya, Raghavender Rao,Patil, Kalpesh,Chirumarry, Sridhar,Jang, Kiwan,Yoon, Yong-Jin,Falck, John R.,Shin, Dong-Soo
supporting information, p. 7089 - 7093 (2015/12/01)
A method involving iron catalyzed acylative cleavage of cyclic and acyclic ethers with acyl/aroyl chlorides has been studied to produce chloroesters and esters respectively. Examination of the scope revealed that less electron rich alkyl group in unsymmetric, acyclic ether was acylated while the chloride derived from the counterpart moiety was volatile and difficult to isolate. In contrast, α-branched cyclic ethers were converted to the corresponding primary ester and secondary chloride. Steric hindrance of ether also plays an important role in acylative C-O bond cleavage. The mechanism of ether cleavage is proposed to involve a single electron initiated SN1 dissociative pathway.
