204192-45-0

Basic information

• Product Name: 2-FLUORO-4-(PIPERAZIN-1-YL)BENZONITRILE
• Synonyms: 2-FLUORO-4-(PIPERAZIN-1-YL)BENZONITRILE
• CAS NO: 204192-45-0
• Molecular Formula: C₁₁H₁₂FN₃
• Molecular Weight: 205.23
• Mol File: 204192-45-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-FLUORO-4-(PIPERAZIN-1-YL)BENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-FLUORO-4-(PIPERAZIN-1-YL)BENZONITRILE(204192-45-0)
• EPA Substance Registry System: 2-FLUORO-4-(PIPERAZIN-1-YL)BENZONITRILE(204192-45-0)

Safety Data

• Hazardous Substances Data: 204192-45-0(Hazardous Substances Data)

Upstream product

• 110-85-0 piperazine 
• 3939-09-1 2,4-difluorobenzonitrile 

Downstream Products

• 1367365-58-9 4-[4-[2-[5-amino-8-(2-furyl)-1-methyl-2-oxo-[1,2,4]triazolo[5,1-i]purin-3-yl]ethyl]piperazin-1-yl]-2-fluoro-benzonitrile 
• 204192-38-1 2-fluoro-4-(trans)-(4-(3'H-spiro[cyclohex-1,1'-isobenzofuran]-4-yl)piperazin-1-yl)benzonitrile 

Relevant articles and documents

SUBSTITUTED PIPERIDINE DERIVATIVES AS SOMATOSTATIN SST1 RECEPTOR ANTAGONISTS

Compound of the formula (I) wherein R1, R2, n and m are as defined in the specification. The compounds of formula (I) are somatostatin sst1 receptor antagonists.

2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists

Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein R is R1, R2, R3, R4 and R5 are H, alkyl or alkoxyalkyl; R6 is H, alkyl, hydroxyalkyl or —CH2F; R7, R8 and R9 are H, alkyl, alkoxy, alkylthio, alkoxyalkyl, halo or —CF3; and Z is optionally substituted aryl, heteroaryl or heteroaryl-alkyl are disclosed. Also disclosed is the use of compounds of formula I in the treatment of central nervous system diseases, in particular Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, and pharmaceutical compositions comprising them.