204582-16-1

Basic information

• Product Name: (4R,5R)-4-methyl-5-phenyl-1,3-dioxolan-2-one
• Synonyms: (4R,5R)-4-methyl-5-phenyl-1,3-dioxolan-2-one
• CAS NO: 204582-16-1
• Molecular Weight: 178.188
• Mol File: 204582-16-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (4R,5R)-4-methyl-5-phenyl-1,3-dioxolan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5R)-4-methyl-5-phenyl-1,3-dioxolan-2-one(204582-16-1)
• EPA Substance Registry System: (4R,5R)-4-methyl-5-phenyl-1,3-dioxolan-2-one(204582-16-1)

Safety Data

• Hazardous Substances Data: 204582-16-1(Hazardous Substances Data)

Upstream product

• 40421-51-0 (1R,2R)-1-phenylpropane-1,2-diol 
• 616-38-6 carbonic acid dimethyl ester 
• 183184-05-6 (4R,5R)-4-methyl-5-phenyl-[1,3,2]dioxathiolane 2-oxide 
• 108-59-8 malonic acid dimethyl ester 
• 124-38-9 carbon dioxide 
• 14212-54-5 (+)-(R,R)-β-methylstyrene oxide 
• 141-97-9 ethyl acetoacetate 
• 609-02-9 methyl-malonic acid dimethylester 

Downstream Products

• 133735-64-5 (1S,2R)-(+)-1-amino-1-phenyl-2-propanol hydrochloride 
• 167083-50-3 (1S,2R)-1-azido-1-phenylpropane-2-ol 

Relevant articles and documents

A Bimetallic Aluminium(Salphen) Complex for the Synthesis of Cyclic Carbonates from Epoxides and Carbon Dioxide

A bimetallic aluminium(salphen) complex is reported as a sustainable, efficient and inexpensive catalyst for the synthesis of cyclic carbonates from epoxides and carbon dioxide. In the presence of this complex and tetrabutylammonium bromide, terminal and internal epoxides reacted at 50 °C and 10 bar carbon dioxide pressure to afford their corresponding cyclic carbonates in yields of 50–94 % and 30–71 % for terminal and internal cyclic carbonates, respectively. Mechanistic studies using deuterated epoxides and an analogous monometallic aluminium(salphen) chloride complex support a mechanism for catalysis by the bimetallic complex, which involves intramolecular cooperative catalysis between the two aluminium centres.

Reaction of 1,2-cyclic sulfites with some soft nucleophiles. Formation of enantiomerically pure γ-lactones

The reaction between 1,2-cyclic sulfites and soft carbon centered nucleophiles has been investigated. For monosubstituted cyclic sulfites, the main products were γ-lactones or acetoxy esters. For 1,2-disubstituted cyclic sulfites, cyclopropanes, carbonate and dioxolanes were the main products. A mechanistic rationale for the product formation is presented. Acta Chemica Scandinavica 1998.