20488-61-3Relevant articles and documents
Design of phase-transition molecular solar thermal energy storage compounds: compact molecules with high energy densities
Qiu, Qianfeng,Gerkman, Mihael A.,Shi, Yuran,Han, Grace G. D.
, p. 9458 - 9461 (2021/09/22)
A series of compact azobenzene derivatives were investigated as phase-transition molecular solar thermal energy storage compounds that exhibit maximum energy storage densities around 300 J g?1. The relative size and polarity of the functional g
Modified mesoporous y zeolite catalyzed nitration of azobenzene using NO2as the nitro source combined with density functional theory studies
Chen, Lei,Guo, Chuanzhou,Guo, Jiaming,Peng, Xinhua
, p. 21389 - 21394 (2021/12/04)
A modified mesoporous Y zeolite is developed to catalyze high ortho regioselective nitration of azobenzene with NO2 as the nitro source. The mesoporous Y zeolite is modified by the ion exchange method and characterized by various analyses involving FT-IR spectroscopy, and XPS and BET analyses. The ortho/para ratio of mononitration products is improved from 0.70 to 2.39 in the presence of the catalyst. Based on density functional theory (DFT), the active sites of nitration reaction are calculated by combining the electrostatic potential with the average local ionization energy, which are further support the electrophilic substitution mechanism of azobenzene in the catalytic nitration reaction. This journal is
A photochromic agonist for μ-opioid receptors
Schoenberger, Matthias,Trauner, Dirk
, p. 3264 - 3267 (2014/04/03)
Opioid receptors (ORs) are widely distributed in the brain, the spinal cord, and the digestive tract and play an important role in nociception. All known ORs are G-protein-coupled receptors (GPCRs) of family A. Another well-known member of this family, rhodopsin, is activated by light through the cis/trans isomerization of a covalently bound chromophore, retinal. We now show how an OR can be combined with a synthetic azobenzene photoswitch to gain light sensitivity. Our work extends the reach of photopharmacology and outlines a general strategy for converting Family A GPCRs, which account for the majority of drug targets, into photoreceptors. Lighting up the opioid receptor: Photofentanyl-2 is a photochromic version of the well-known analgesic fentanyl. It is a potent agonist in the dark (or when illuminated with blue light) and loses activity when irradiated with UV light. It can be used to optically control the μ-opioid receptor, converting a G-protein-coupled receptor (GPCR) into a photoreceptor.