204919-70-0

Basic information

• Product Name: Benzonitrile, 3-ethynyl-4-methoxy- (9CI)
• Synonyms: Benzonitrile, 3-ethynyl-4-methoxy- (9CI);3-Ethynyl-4-methoxybenzonitrile
• CAS NO: 204919-70-0
• Molecular Formula: C₁₀H₇NO
• Molecular Weight: 157.16868
• Product Categories: METHOXY
• Mol File: 204919-70-0.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzonitrile, 3-ethynyl-4-methoxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 3-ethynyl-4-methoxy- (9CI)(204919-70-0)
• EPA Substance Registry System: Benzonitrile, 3-ethynyl-4-methoxy- (9CI)(204919-70-0)

Safety Data

• Hazardous Substances Data: 204919-70-0(Hazardous Substances Data)

Upstream product

• 117572-79-9 3-bromo-4-methoxybenzonitrile 
• 914106-26-6 4-chloro-3-iodobenzonitrile 
• 914106-25-5 4-chloro-3-iodobenzaldoxime 
• 914106-33-5 4-chloro-3-(3-hydroxy-3-methylbut-1-ynyl)benzonitrile 
• 914106-30-2 4-methoxy-4-[2-(trimethylsilyl)ethynyl]benzonitrile 
• 276866-90-1 4-chloro-3-iodobenzaldehyde 

Downstream Products

• 914106-20-0 3-(4-cyano-2-nitrophenyl)-5-(5-cyano-2-methoxyphenyl)isoxazole 
• 914106-21-1 3-(4-cyano-2-methoxyphenyl)-5-(5-cyano-2-methoxyphenyl)isoxazole 
• 914106-24-4 3,5-bis(5-cyano-2-methoxyphenyl)isoxazole 
• 1072911-80-8 2-(5-cyano-2-methoxyphenyl)benzofuran-5-carbonitrile 
• 1072911-83-1 2-(5-cyano-2-methoxyphenyl)benzofuran-6-carbonitrile 
• 1269604-62-7 C₂₈H₂₅NO₅ 
• 1269604-44-5 C₂₈H₂₀N₂O₄ 
• 1269604-45-6 C₂₆H₁₉NO₃ 
• 378751-64-5 3-oxo-2,3-dihydrobenzofuran-5-carbonitrile 
• 1201666-88-7 4-(5-cyano-2-methoxyphenyl)-1-(3-cyanophenyl)-1H-1,2,3-triazole 
• 1201666-90-1 4-(5-cyano-2-methoxyphenyl)-1-(4-cyanophenyl)-1H-1,2,3-triazole 
• 914105-84-3 5-(4-cyano-2-methoxyphenyl)-3-(4-cyanophenyl)isoxazole 

Relevant articles and documents

Practical, modular, and general synthesis of 3-coumaranones through gold-catalyzed intermolecular alkyne oxidation strategy

A gold-catalyzed intermolecular alkyne oxidation for the preparation of 3-coumaranones has been developed. Using 8-isopropylquinoline N-oxides as oxidants, the reactions of o-ethynylanisoles afford versatile 3-coumaranones in moderate to good isolated yields. The synthetic utility of this chemistry is also indicated by the synthesis of the natural product sulfuretin.

Synthesis and antiprotozoal activity of dicationic 3,5-diphenylisoxazoles

Novel dicationic 3,5-diphenylisoxazole compounds are described. Synthetic routes to these novel compounds are provided. Several of the compounds displayed in vitro activity versus Trypanosoma brucei brucei and Plasmodium falciparum comparable to that of furamidine. A majority of the novel compounds also were less toxic to VERO cells than furamidine.