914106-26-6 Usage
Description
4-Chloro-3-Iodobenzonitrile is an organic compound characterized by the presence of a chlorine atom at the 4-position and an iodine atom at the 3-position on a benzene ring, with a nitrile group attached. This unique molecular structure endows it with specific chemical properties that make it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
4-Chloro-3-Iodobenzonitrile is used as a key intermediate in the synthesis of 3,5-diphenylisoxazoles, which are known for their antimicrobial properties. These compounds are valuable in the development of new drugs to combat bacterial infections, particularly in the context of increasing antibiotic resistance.
In the synthesis process, 4-chloro-3-iodobenzonitrile serves as a starting material, which can be further reacted to form the desired 3,5-diphenylisoxazole derivatives. These derivatives exhibit broad-spectrum antimicrobial activity, making them potential candidates for use in pharmaceutical formulations to treat various bacterial infections.
Overall, 4-chloro-3-iodobenzonitrile plays a crucial role in the development of new antimicrobial agents, contributing to the ongoing efforts to address the global challenge of antibiotic resistance and improve public health.
Check Digit Verification of cas no
The CAS Registry Mumber 914106-26-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,4,1,0 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 914106-26:
(8*9)+(7*1)+(6*4)+(5*1)+(4*0)+(3*6)+(2*2)+(1*6)=136
136 % 10 = 6
So 914106-26-6 is a valid CAS Registry Number.
914106-26-6Relevant articles and documents
Synthesis and in vitro antiprotozoal activities of dicationic 3,5-diphenylisoxazoles
Patrick, Donald A.,Bakunov, Stanislav A.,Bakunova, Svetlana M.,Kumar, E.V.K. Suresh,Lombardy, Richard J.,Jones, Susan Kilgore,Bridges, Arlene S.,Zhirnov, Oksana,Hall, James Edwin,Wenzler, Tanja,Brun, Reto,Tidwell, Richard R.
, p. 2468 - 2485 (2008/02/03)
3,5-Bis(4-amidinophenyl)isoxazole (3) - an analogue of 2,5-bis(4- amidinophenyl)furan (furamidine) in which the central furan ring is replaced by isoxazole - and 42 novel analogues were prepared by two general synthetic pathways. The 43 isoxazole derivati