20576-82-3 Usage
Description
4-(TERT-BUTOXYCARBONYL)BENZOIC ACID, also known as Mono-tert-Butyl Terephthalate, is an organic compound with the molecular formula C11H12O4. It is a derivative of benzoic acid, featuring a tert-butoxycarbonyl group attached to the 4-position of the benzene ring. 4-(TERT-BUTOXYCARBONYL)BENZOIC ACID is known for its potential applications in various industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
4-(TERT-BUTOXYCARBONYL)BENZOIC ACID is used as a synthetic intermediate for the development of pyrrolidinone analogs. These analogs act as potential 20S proteasome inhibitors, which are crucial in the regulation of cellular processes such as protein degradation and cell cycle progression. Inhibition of the 20S proteasome can lead to the disruption of these processes, making it a promising approach for the treatment of various diseases, including cancer.
In the synthesis of pyrrolidinone analogs, 4-(TERT-BUTOXYCARBONYL)BENZOIC ACID serves as a key building block, providing the necessary structural framework for the development of these potential therapeutic agents. The compound's reactivity and functional groups enable the formation of various derivatives, which can be further optimized for improved potency and selectivity against the 20S proteasome.
Additionally, 4-(TERT-BUTOXYCARBONYL)BENZOIC ACID may also find applications in other industries, such as materials science, where its unique chemical properties could be utilized for the development of novel materials with specific properties. However, further research and development would be required to explore these potential applications fully.
Check Digit Verification of cas no
The CAS Registry Mumber 20576-82-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,5,7 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20576-82:
(7*2)+(6*0)+(5*5)+(4*7)+(3*6)+(2*8)+(1*2)=103
103 % 10 = 3
So 20576-82-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O4/c1-12(2,3)16-11(15)9-6-4-8(5-7-9)10(13)14/h4-7H,1-3H3,(H,13,14)
20576-82-3Relevant articles and documents
Unraveling the Self-Assembly Modes in Multicomponent Supramolecular Gels Using Single-Crystal X-ray Diffraction
Damodaran, Krishna K.,Farahani, Abbas D.,Ghosh, Dipankar,Martin, Adam D.,Thordarson, Pall
, (2021/06/14)
The control and prediction of the self-assembly process in multicomponent supramolecular gels are challenging because the structure and properties rely mostly on the geometry and spatial arrangement of the building blocks. The understanding of noncovalent
Synthesis and biological activity of optimized belactosin C congeners
Korotkov, Vadim S.,Ludwig, Antje,Larionov, Oleg V.,Lygin, Alexander V.,Groll, Michael,De Meijere, Armin
scheme or table, p. 7791 - 7798 (2011/12/05)
Successful biochemical studies of the natural products belactosin A and C as well as their more stable acylated derivatives have proved them to be powerful proteasome inhibitors and thereby potential candidates as pharmacologically relevant active compoun
Creation of superior carboxyfluorescein dyes by blocking donor-excited photoinduced electron transfer
Mineno, Tomoko,Ueno, Tasuku,Urano, Yasuteru,Kojima, Hirotatsu,Nagano, Tetsuo
, p. 5963 - 5966 (2007/10/03)
(Chemical Equation Presented) Carboxyfluoresceins are widely utilized as fluorescence labeling reagents, but we recently found that their emission intensity is markedly decreased after esterification. On the basis of our hypothesis that the fluorescence d
