313269-51-1

Basic information

• Product Name: tert-butyl 4-[(2,4-diaminoquinazolin-6-yl)methoxycarbonyl]benzoate
• Synonyms: tert-butyl 4-[(2,4-diaminoquinazolin-6-yl)methoxycarbonyl]benzoate
• CAS NO: 313269-51-1
• Molecular Weight: 394.43
• Mol File: 313269-51-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-[(2,4-diaminoquinazolin-6-yl)methoxycarbonyl]benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-[(2,4-diaminoquinazolin-6-yl)methoxycarbonyl]benzoate(313269-51-1)
• EPA Substance Registry System: tert-butyl 4-[(2,4-diaminoquinazolin-6-yl)methoxycarbonyl]benzoate(313269-51-1)

Safety Data

• Hazardous Substances Data: 313269-51-1(Hazardous Substances Data)

Upstream product

• 98747-29-6 2,4-diaminoquinazoline-6-methanol 
• 100-20-9 terephthaloyl chloride 
• 28313-42-0 di-tert-butyl terephthalate 
• 20576-82-3 terephthalic acid mono-tert-butyl ester 

Relevant articles and documents

Computational predictions of binding affinities to dihydrofolate reductase: Synthesis and biological evaluation of methotrexate analogues

The relative binding affinities to human dihydrofolate reductase of four new potential antifolates, containing ester linkages between the two aromatic systems, were estimated by free energy perturbation simulations. The ester analogue, predicted to exhibi