206141-58-4

Basic information

• Product Name: 1,5-bis(4-hydroxy-3-methoxybenzaldehyde)carbohydrazone
• CAS NO: 206141-58-4
• Molecular Weight: 358.354
• Mol File: 206141-58-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,5-bis(4-hydroxy-3-methoxybenzaldehyde)carbohydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-bis(4-hydroxy-3-methoxybenzaldehyde)carbohydrazone(206141-58-4)
• EPA Substance Registry System: 1,5-bis(4-hydroxy-3-methoxybenzaldehyde)carbohydrazone(206141-58-4)

Safety Data

• Hazardous Substances Data: 206141-58-4(Hazardous Substances Data)

Upstream product

• 497-18-7 carbonodihydrazide 
• 121-33-5 vanillin 

Downstream Products

• 100327-64-8 Sb((C₆H₃(OH)(OCH₃)CHNNH)2CO)2Cl₂⁽¹⁺⁾*Cl^(1-)={Sb((C₆H₃(OH)(OCH₃)CHNNH)2CO)2Cl₂}Cl 

Relevant articles and documents

Carbonyl dihydrazone derivative, preparation method and applications thereof

The invention relates to a carbonyl dihydrazone derivative represented by a chemical structural formula I, and a pharmaceutically acceptable salt thereof, a pharmaceutical composition and applicationsin preparation of influenza virus neuraminidase inhibitors, wherein the formula I is defined in the specification, and R is selected from hydroxyl, dihydroxyl, 2-hydroxyl-3-methoxy, 2-hydroxyl-4-methoxy, 2-hydroxyl-5-methoxy, 2-hydroxyl-6-methoxy, 3-hydroxyl-2-methoxy, 3-hydroxyl-4-methoxy, 3-hydroxyl-5-methoxy, 3-hydroxyl-6-methoxy, 4-hydroxyl-2-methoxy, 4-hydroxyl-3-methoxy, 4-hydroxy-3,5-dimethoxy, 2-hydroxy-3-ethoxy, 2-hydroxy-4-ethoxy, 2-hydroxy-5-ethoxy, 2-hydroxy-6-ethoxy, 3-hydroxy-2-ethoxy, 3-hydroxy-4-ethoxy, 3-hydroxy-5-ethoxy, 3-hydroxy-6-ethoxy, 4-hydroxy-2-ethoxy, 4-hydroxy-3-ethoxy, 4-hydroxy-3,5-diethoxy, trihydroxy and 4-hydroxy-3,5-dimethyl.

Green synthetic method for 1,5-disubstituted carbohydrazones

A green synthetic method for 1,5-disubstituted carbohydrazones is described. The reaction of dimethyl carbonate with hydrazine hydrate first gave carbohydrazide, which further reacted with various aromatic aldehydes or aliphatic ketones under solvent-free conditions to efficiently afford 1,5-disubstituted carbohydrazone. This protocol has the advantages of using nontoxic dimethyl carbonate as starting material, no use of organic solvents, short reaction time, high yield, and simple workup procedure. Copyright Taylor & Francis Group, LLC.