206434-76-6

Basic information

• Product Name: 6-methoxy-2-(4-methoxyphenyl)-3-(4-nitrobenzoyl)-benzo[b]thiophene
• Synonyms: 6-methoxy-2-(4-methoxyphenyl)-3-(4-nitrobenzoyl)-benzo[b]thiophene
• CAS NO: 206434-76-6
• Molecular Weight: 419.458
• Mol File: 206434-76-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-methoxy-2-(4-methoxyphenyl)-3-(4-nitrobenzoyl)-benzo[b]thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-2-(4-methoxyphenyl)-3-(4-nitrobenzoyl)-benzo[b]thiophene(206434-76-6)
• EPA Substance Registry System: 6-methoxy-2-(4-methoxyphenyl)-3-(4-nitrobenzoyl)-benzo[b]thiophene(206434-76-6)

Safety Data

• Hazardous Substances Data: 206434-76-6(Hazardous Substances Data)

Upstream product

• 14922-36-2 4-nitrophenylglyoxylic acid 
• 1163701-10-7 (5-methoxy-2-((4-methoxyphenyl)ethynyl)phenyl)(methyl)-sulfane 
• 122-04-3 4-nitro-benzoyl chloride 
• 63675-74-1 2-(4'-methoxyphenyl)-6-methoxybenzothiophene 

Downstream Products

• 84541-38-8 [6-Methoxy-2-(4-Methoxyphenyl)benzo[b]thien-3-yl]-[4-[2-(1-Piperidinyl)ethoxy]phenyl] Methanone 

Relevant articles and documents

Nucleophilic aromatic substitution on 3-aroyl-2-arylbenzothiophenes. Rapid access to raloxifene and other selective estrogen receptor modulators

Versatile, mild and high yielding methods for nucleophilic aromatic substitution of 2-dialkylamino-1-ethoxides and related nucleophiles on 3- aroyl-2-arylbenzothiophene nuclei are presented. A short synthesis of raloxifene is detailed.

Substituted benzo(b)thiophene compounds having activity as selective estrogen receptor modulators

The present invention provides compounds with nitrogen, sulfur or carbon linked basic side chains of formula where R1and R2are independently hydrogen, halo, hydroxy, alkoxy, alkylcarbonyloxy, alkoxycarbonyl, alkoxycarbonyloxy, arylca