20822-87-1

Basic information

• Product Name: 1-O-acetyl-2,3,5-tri-O-benzoyl-α-D-xylofuranose
• Synonyms: 1-O-acetyl-2,3,5-tri-O-benzoyl-α-D-xylofuranose
• CAS NO: 20822-87-1
• Molecular Weight: 504.493
• Mol File: 20822-87-1.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: 1-O-acetyl-2,3,5-tri-O-benzoyl-α-D-xylofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-acetyl-2,3,5-tri-O-benzoyl-α-D-xylofuranose(20822-87-1)
• EPA Substance Registry System: 1-O-acetyl-2,3,5-tri-O-benzoyl-α-D-xylofuranose(20822-87-1)

Safety Data

• Hazardous Substances Data: 20822-87-1(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 120964-98-9 methyl 2,3,5-tri-O-benzoyl-αβ-D-xylbofuranoside 
• 22250-06-2 1,2-O-Cyclohexylidene-α-D-xylofuranose 
• 73488-45-6 1,2:3,5-di-O-cyclohexylidene-α-D-xylofuranose 
• 159495-21-3 5-O-benzoyl-1,2-O-cyclohexylidene-3-O-p-toluenesulfonyl-α-D-xylofuranose 
• 41546-19-4 α-L-lyxose 
• 69350-76-1 methyl 2,3,5-tri-O-benzoyl-αβ-D-ribofuranoside 
• 171866-28-7 1-O-methyl-2,3,5-tri-O-benzoyl-L-ribofuranose 
• 64-19-7 acetic acid 
• 13039-67-3 (2S,3S,4S)-2-(hydroxymethyl)-5-methoxyoxolane-3,4-diol 
• 609-06-3 L-xylose 
• 1173695-22-1 1-O-acetyl-2,3,5-tri-O-benzoyl-α-L-ribofuranose 
• 24259-59-4 L-ribose 
• 98-88-4 benzoyl chloride 

Downstream Products

• 90301-38-5 2,3,5-tri-O-benzoyl-α-D-lyxofuranosyl cyanide 
• 109923-74-2 2',3',5'-tri-Obenzoyl-L-cytidine 
• 192133-14-5 C₃₂H₂₆O₇Se 
• 109923-78-6 6-N-benzoyl-2',3',5'-tri-O-benzoyl-β-L-adenosine 
• 65-46-3 L-cytidine 
• 58-61-7 L-adenosine 
• 171866-29-8 1-bromo-2-deoxy-2-β-fluoro-3,5-di-O-benzoyl-α-L-arabinose 
• 58-96-8 L-uridine 
• 171721-00-9 1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-L-arabinofuranose 
• 171720-99-3 1,3,5-tri-O-benzoyl-2-O-(2-imidazolylsulfonyl)-α-L-ribofuranose 
• 163252-36-6 clevudine 
• 171721-03-2 1-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-β-L-arabinofuranosyl)thymine 
• 99355-32-5 C₃₁H₂₅N₅O₇S 
• 99355-33-6 C₃₁H₂₅N₅O₇S 

Relevant articles and documents

L-nucleoside compounds and application thereof

The invention discloses L-nucleoside compounds having the structure characteristic represented by the formula (I) or pharmaceutically acceptable salts thereof, and belongs to the technical field of pharmaceutical chemistry. The compounds can inhibit the activity of RNA viral polymerase, so the compounds can be used as potential drugs for prevention and treatment of infection of RNA viruses such as HCV, influenza virus, HRV (rhinovirus), RSV, Ebola virus, dengue virus, intestinal virus and the like.

METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE

An object of the present invention is to provide a industrially appropriate method for producing the β-anomers of ribofuranose derivatives in a highly selective manner at a high yield. The present invention provides a method for producing ribofuranose derivatives wherein β-anomers is precipitated from among the generated furanose derivatives by controlling the amount of a reaction reagent used and/or using a poor solvent in the acetolysis reactions of 2,3,5-tri-O-acyl-1-O-alkyl-ribofuranose and 2,3-di-O-acyl-1-O-alkyl-5-deoxy-ribofuranose.

Reaction kinetics and mechanism of acid-catalyzed anomerization of 1-O-acetyl-2,3,5-tri-O-benzoyl-l-ribofuranose

The mechanism of the acid-catalyzed anomerization of 1-O-acetyl-2,3,5-O-benzoyl-α- and -β-l-ribofuranoses in different acetic acid-acetic anhydride mixtures was investigated. The progress of the reactions was followed by NMR spectroscopy and the rate cons