2085-90-7Relevant articles and documents
Selective mono addition of aryllithiums to dialdehydes by micromixing
Nagaki, Aiichiro,Yamashita, Hiroki,Takahashi, Yusuke,Ishiuchi, Satoshi,Imai, Keita,Yoshida, Jun-Ichi
supporting information, p. 71 - 73 (2018/01/26)
Micromixing enables highly selective mono addition of aryllithiums to dialdehydes. Because the unchanged formyl group in the products can be used for further transformations, the present approach serves as a powerful method for protecting-group-free synthesis.
Arene-promoted lithiation of 1,n-dihaloalkanes (n=2-6): a comparative study
Abou, Abdeslam,Foubelo, Francisco,Yus, Miguel
, p. 10417 - 10424 (2007/10/03)
The reaction of 1,n-dichloroalkanes 3a (n=2-6) with an excess of lithium powder and a catalytic amount of 4,4′-di-tert-butylbiphenyl (DTBB; 2.5 mol %) in the presence of different carbonyl compounds [ButCHO, PhCHO, Et2CO, (CH2/
Highly diastereoselective tandem reduction-allylation reactions of 1,4-diketones with zirconocene-olefin complexes
Fujita, Kazuya,Shinokubo, Hiroshi,Oshima, Koichiro
, p. 2550 - 2552 (2007/10/03)
Terminal alkenes act as dual nucleophiles in a zirconocene-mediated, highly 1,4-diastereoselective, tandem reduction-allylation reaction of 1,4-diketones. A zirconocene-alkene complex (in equilibrium with an allyl-zirconocene-hydride species) can deliver both hydride and an allyl group to a diketone, with control of the relative configuration of up three new stereogenic centers (see scheme).