209286-97-5

Basic information

• Product Name: 2-IODO-PYRIDIN-3-YLAMINE
• Synonyms: 2-IODO-PYRIDIN-3-YLAMINE;2-iodine-3-aminopyridine;2-Iodo-3-pyridinamine;2-iodopyridin-3-aMine;2-Iodo-3-aMinopyridine;2-Lodo-pyridin-3-ylaMine
• CAS NO: 209286-97-5
• Molecular Formula: C5H5IN2
• Molecular Weight: 220.01
• EINECS: -0
• Product Categories: Pyridine
• Mol File: 209286-97-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 327.2 °C at 760 mmHg
• Flash Point: 151.7 °C
• Appearance: /
• Density: 2.055g/cm³
• Vapor Pressure: 0.000205mmHg at 25°C
• Refractive Index: 1.702
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 2.78±0.10(Predicted)
• CAS DataBase Reference: 2-IODO-PYRIDIN-3-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODO-PYRIDIN-3-YLAMINE(209286-97-5)
• EPA Substance Registry System: 2-IODO-PYRIDIN-3-YLAMINE(209286-97-5)

Safety Data

• Hazardous Substances Data: 209286-97-5(Hazardous Substances Data)

Usage

General Description

2-IODO-PYRIDIN-3-YLAMINE is a chemical compound with the molecular formula C5H5IN2. It is a derivative of pyridine, which is commonly used in the synthesis of pharmaceuticals and agrochemicals. 2-IODO-PYRIDIN-3-YLAMINE is known for its versatile reactivity and has been utilized in various organic transformations, including cross-coupling reactions and metal-catalyzed reactions. It has also shown potential as a building block in the synthesis of biologically active molecules. Additionally, 2-IODO-PYRIDIN-3-YLAMINE has been studied for its potential applications in material science and biomedical research. Overall, this chemical compound has garnered interest in the scientific community for its synthetic utility and potential biological activities.

InChI:InChI=1/C5H5IN2/c6-5-4(7)2-1-3-8-5/h1-3H,7H2

Upstream product

• 209286-96-4 2-iodo-3-nitropyridine 
• 39856-58-1 3-amino-2-bromopyridine 
• 462-08-8 pyridin-3-ylamine 

Downstream Products

• 1450658-27-1 methyl 2-methyl-1-(1-phenylethyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxylate 
• 1450658-28-2 2-methyl-1-(1-phenylethyl)-1H-pyrrolo-[3,2-b]pyridine-3-carboxylic acid 
• 1450651-62-3 N-((2-hydroxy-4,6-dimethylpyridin-3-yl)methyl)-2-methyl-1-(1-phenylethyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxamide 

Relevant articles and documents

A High-Throughput Assay for Arylamine Halogenation Based on a Peroxidase-Mediated Quinone-Amine Coupling with Applications in the Screening of Enzymatic Halogenations

Arylhalides are important building blocks in many fine chemicals, pharmaceuticals and agrochemicals, and there has been increasing interest in the development of more "green" halogenation methods based on enzyme catalysis. However, the screening and development of new enzymes for biohalogenation has been hampered by a lack of high-throughput screening methods. Described herein is the development of a colorimetric assay for detecting both chemical and enzymatic arylamine halogenation reactions in an aqueous environment. The assay is based on the unique UV/Vis spectrum created by the formation of an ortho-benzoquinone-amine adduct, which is produced by the peroxidase-catalysed benzoquinone generation, followed by Michael addition of either a halogenated or non-halogenated arylamine. This assay is sensitive, rapid and amenable to high-throughput screening platforms. We have also shown this assay to be easily coupled to a flavin-dependent halogenase, which currently lacks any convenient colorimetric assay, in a "one-pot" workflow.

Sulfonic acid sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds

The compounds of formula I herein exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More specifically, they are inhibitors of the activity of Factor Xa. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, and their use, for treating a patient suffering from, or subject to, a physiological condition which can be ameliorated by the administration of an inhibitor of the activity of Factor Xa.