209802-54-0

Basic information

• Product Name: 2H-Pyrrol-2-one, 1,5-dihydro-4-methyl-5-(2-methylpropylidene)-, (5Z)- (9CI)
• Synonyms: 2H-Pyrrol-2-one, 1,5-dihydro-4-methyl-5-(2-methylpropylidene)-, (5Z)- (9CI)
• CAS NO: 209802-54-0
• Molecular Formula: C9H13NO
• Molecular Weight: 151.20562
• Product Categories: ALCOHOL
• Mol File: 209802-54-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-Pyrrol-2-one, 1,5-dihydro-4-methyl-5-(2-methylpropylidene)-, (5Z)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrrol-2-one, 1,5-dihydro-4-methyl-5-(2-methylpropylidene)-, (5Z)- (9CI)(209802-54-0)
• EPA Substance Registry System: 2H-Pyrrol-2-one, 1,5-dihydro-4-methyl-5-(2-methylpropylidene)-, (5Z)- (9CI)(209802-54-0)

Safety Data

• Hazardous Substances Data: 209802-54-0(Hazardous Substances Data)

Upstream product

• 598-23-2 3-methyl-but-1-yne 
• 34450-60-7 (Z)-3-iodobut-2-enoic acid 
• 2393-23-9 4-methoxy-benzylamine 
• 623-56-3 5-methyl-3-hexanone 
• 443680-34-0 4-methyl-2-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester 
• 616-02-4 citraconic acid anhydride 
• 1072-87-3 citraconimide 
• 79641-88-6 1,5-dihydro-5-hydroxy-4-methyl-2H-pyrrol-2-one 
• 443680-35-1 2-(1-hydroxy-2-methylpropyl)-3-methyl-5-oxo-2,5-dihydropyrrole-1-carboxylic acid tert-butyl ester 
• 608533-05-7 (5E)-1-(2,4-dimethoxybenzyl)-4-methyl-5-(2-methylpropylidene)-3-pyrrolin-2-one 
• 752222-91-6 5-hydroxy-4-methyl-2-pyrrolidinone 
• 53598-99-5 4-methyl-2,5-dihydro-1H-pyrrol-2-one 
• 906647-93-6 tert-butyl 6-oxo-3a,4,6,6a-tetrahydropyrrolo[3,4-c]pyrazole-5(3H)-carboxylate 
• 53507-06-5 N-(2-methylprop-2-en-1-yl)prop-2-enamide 

Relevant articles and documents

A facile synthesis of CD45 protein tyrosine phosphatase inhibitor marine natural product pulchellalactam

A facile five-step route to the naturally occurring CD45 protein tyrosine phosphatase inhibitor, (Z)-pulchellalactam, with 64% overall yield has been demonstrated starting from citraconimide (5) via regioselective NaBH4 reduction, catalytic hydrogenation, resin-catalyzed dehydration, W-BOC protection, and stereoselective condensation pathway.

Total synthesis of pulchellalactam via an RCM strategy

Total synthesis of (Z) pulchellalactam, a CD protein tyrosine phosphatase inhibitor, from commercially available methallyl chloride employing ring-closure metathesis (RCM) as a key step is described. Copyright Taylor & Francis Group, LLC.

Straightforward Access to a Great Diversity of Complex Biorelevant γ-Lactams Thanks to a Tunable Cascade Multicomponent Process

This reviews surveys the preparation of a great diversity of complex biorelevant γ-lactam backbones thanks to scalable copper(I)-catalyzed cascade multicomponent processes.

Short synthesis of pulchellalactam

tert -Butyl 4-methyl-2-oxo-2,5-dihydro-1 H -pyrrole-1-carboxylate 4 was synthesized by a short two-step procedure: regioselective 1,3-dipolar diazomethane cycloaddition to N -Boc-pyrrolinone 2 and thermolysis of the adduct. The compound 4 could be converted in one step into pulchellalactam. Copyright Taylor & Francis Group, LLC.