608533-05-7

Basic information

• Product Name: (5E)-1-(2,4-dimethoxybenzyl)-4-methyl-5-(2-methylpropylidene)-3-pyrrolin-2-one
• CAS NO: 608533-05-7
• Molecular Weight: 301.386
• Mol File: 608533-05-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5E)-1-(2,4-dimethoxybenzyl)-4-methyl-5-(2-methylpropylidene)-3-pyrrolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5E)-1-(2,4-dimethoxybenzyl)-4-methyl-5-(2-methylpropylidene)-3-pyrrolin-2-one(608533-05-7)
• EPA Substance Registry System: (5E)-1-(2,4-dimethoxybenzyl)-4-methyl-5-(2-methylpropylidene)-3-pyrrolin-2-one(608533-05-7)

Safety Data

• Hazardous Substances Data: 608533-05-7(Hazardous Substances Data)

Upstream product

• 623-56-3 5-methyl-3-hexanone 
• 79-36-7 dichloroacethyl chloride 

Downstream Products

• 209802-54-0 (E)-pulchellalactam 

Relevant articles and documents

Metal-catalysed radical cyclisations leading to N-heterocycles: New approaches to gabapentin and pulchellalactam

The copper(I) or ruthenium(II)-mediated radical cyclisation of halo-amides has been utilised to afford functionalised pyrrolidinones via 5-endo-trig or 5-exo-trig radical cyclisation pathways. This methodology has been applied to novel and concise syntheses of the anti-epileptic drug gabapentin and the biologically active natural product pulchellalactam.