209981-66-8

Basic information

• Product Name: benzo[d][1,3]dioxol-5-yldiphenylphosphine oxide
• Synonyms: benzo[d][1,3]dioxol-5-yldiphenylphosphine oxide
• CAS NO: 209981-66-8
• Molecular Weight: 322.3
• Mol File: 209981-66-8.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: benzo[d][1,3]dioxol-5-yldiphenylphosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: benzo[d][1,3]dioxol-5-yldiphenylphosphine oxide(209981-66-8)
• EPA Substance Registry System: benzo[d][1,3]dioxol-5-yldiphenylphosphine oxide(209981-66-8)

Safety Data

• Hazardous Substances Data: 209981-66-8(Hazardous Substances Data)

Usage

General Description

Benzo[d][1,3]dioxol-5-yldiphenylphosphine oxide is a chemical compound that consists of a benzo-fused heterocyclic ring attached to a diphenylphosphine oxide group. It is commonly used as a ligand in transition metal catalyzed reactions, particularly in the field of organic synthesis. benzo[d][1,3]dioxol-5-yldiphenylphosphine oxide is known for its ability to activate metal catalysts and facilitate a wide range of chemical transformations, including carbon-carbon and carbon-heteroatom bond forming reactions. Its unique structure and properties make it a valuable tool in the development of new and efficient synthetic routes for the production of complex organic molecules.

Upstream product

• 22026-39-7 benzo[d][1,3]dioxole-5-carbohydrazide 
• 4559-70-0 Diphenylphosphine oxide 
• 16387-85-2 benzo[d][1,3]dioxol-5-yl 4-methylbenzenesulfonate 
• 2635-13-4 1,2-(methylenedioxy)-4-bromobenzene 
• 829-85-6 diphenylphosphane 
• 94-53-1 Piperonylic acid 
• 32745-63-4 phenyl benzo[d][1,3]dioxole-5-carboxylate 
• 717903-52-1 6-(trimethylsilyl)benzo[d][1,3]dioxol-5-yl triflate 
• 94839-07-3 3,4-(methylenedioxy)-benzeneboronic acid 
• 128612-45-3 benzo[d][1,3]dioxol-5-yl methanesulfonate 
• 533-31-3 Sesamol 
• 274-09-9 Methylenedioxybenzene 
• 1499-21-4 Diphenylphosphinic chloride 

Downstream Products

• 209981-67-9 diphenyl(2-iodo-(3,4)-methylenedioxyphenyl)phosphine oxide 

Relevant articles and documents

A cyclodiphosphazane based pincer ligand, [2,6-{μ-(tBuN)2P(tBuHN)PO}2C6H3I]: NiII, PdII, PtII and CuI complexes and catalytic studies

Synthesis and late-transition metal complexes of pincer capable cyclodiphosphazane, 2,6-{μ-(tBuN)2P(tBuHN)PO}2C6H3I (1) are described. The condensation of 2-iodoresorcinol with cis-{ClP(μ-NtBu)2PN(H)tBu} produced a difunctional derivative 1 in good yield. The treatment of Ni(COD)2, Pd2(dba)3·CHCl3 or Pt(PPh3)4 with 1 afforded pincer complexes [2,6-{μ-(tBuN)2P(tBuHN)PO}2C6H3MI] (2 M = Ni; 3 M = Pd and 4 M = Pt). The reaction of complex 3 with copper halides resulted in the formation of heterobimetallic complexes bridged by rhombic {Cu(μ-X)}2 units, [{{Cu(μ-X)}2}{μ-(tBuN)2P(tBuHN)PO}2C6H3PdI] (5 X = I and 6 X = Br). The crystal structures of 1-3, 5 and 6 were established by single X-ray diffraction studies. The palladium complex 3 was tested for catalytic P-arylation of diphenylphosphine oxide (Ph2P(O)H) under microwave irradiation. Moderate to good catalytic activity was observed with aryl bromides. This journal is

NiCl 2as a Cheap and Efficient Precatalyst for the Coupling of Aryl Fluorosulfonate and Phosphite/Phosphine Oxide

Herein, NiCl 2is employed as a cheap precatalyst in the formation of C(sp 2)-P bond via cross-coupling reaction of phenol derivatives and phosphine oxides/phosphites. This catalytic system allows a variety of phenols with diverse functional groups to transform into phosphates with good yields. No additional additive is used in this reaction.

Cu/Picolinamides-Catalyzed Coupling of (Hetero)aryl Halides with Secondary Phosphine Oxides and Phosphite?

Some 4-hydroxy-picolinic acid derived amides were revealed as more efficient ligands for Cu-catalyzed coupling of (hetero)aryl halides with secondary phosphine oxides and phosphites. Only 3—5 mol% CuI and ligands were required to ensure coupling with a number of (hetero)aryl bromides and iodides to complete at 120 oC in 10—20 h.