128612-45-3

Basic information

• Product Name: 1,3-benzodioxol-5-yl methanesulfonate
• Synonyms: 1,3-benzodioxol-5-yl methanesulfonate
• CAS NO: 128612-45-3
• Molecular Formula: C₈H₈O₅S
• Molecular Weight: 216.21112
• Mol File: 128612-45-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 364.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.484±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1,3-benzodioxol-5-yl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-benzodioxol-5-yl methanesulfonate(128612-45-3)
• EPA Substance Registry System: 1,3-benzodioxol-5-yl methanesulfonate(128612-45-3)

Safety Data

• Hazardous Substances Data: 128612-45-3(Hazardous Substances Data)

Upstream product

• 533-31-3 Sesamol 
• 124-63-0 methanesulfonyl chloride 
• 7143-01-3 Methanesulfonic anhydride 

Downstream Products

• 440370-62-7 (1S,3S)-1-[3,4-(methylenedioxy)phenoxy]-8-N-methyl-3-p-tolyl-8-aza-bicyclo[3.2.2]nonane 
• 40804-81-7 2-(benzo[d][1,3]dioxol-5-yl)-1-phenylethan-1-one 
• 4421-09-4 piperonylonitrile 
• 4676-39-5 1-(1,3-benzodioxol-5-yl)-2-propanone 
• 209981-66-8 (benzo[d][1,3]dioxol-5-yl)diphenylphosphine oxide 
• 3315-20-6 2-(3',4'-Methylendioxyphenyl)benzoxazol 
• 35493-08-4 N-(benzo[d][1,3]dioxol-5-yl)-2-methylbenzamide 
• 1099595-82-0 4-trifluoromethyl-1-(3,4-methylenedioxyphenyl)lbenzene 
• 24382-05-6 3,4-methylenedioxybiphenyl 

Relevant articles and documents

Cyanation of unactivated aryl chlorides and aryl mesylates catalyzed by palladium and hemilabile MOP-type ligands

Palladium-catalyzed cyanation of aryl halides and pseudo halides with potassium hexacyanoferrate is described employing the hemilabile, bulky, and electron-rich MOP-type ligands. When the mixture of t-BuOH and H2O was used as the solvent and K2CO3 as the base, the MOP-type ligands showed high efficiency for the palladium-catalyzed cyanation. The effect of ligand structure was studied in detail, and 2-di-tert-butylphosphino-2′-isopropoxy-1,1′-binaphthyl was the more effective for the cyanation. The catalyst system allows the cyanation of unactivated aryl chlorides, and even aryl mesylates to occur in good yields. Furthermore, the reactivity of different arylated reagents in the catalytic system was found to be: ArBr > ArCl >> ArOMs > ArOSO2Im > ArOSO2NMe2.

Nickel-catalyzed C-P coupling of aryl mesylates and tosylates with H(O)PR1R2

A method was developed for the nickel-catalyzed phosphonylation of aryl mesylates and tosylates with H(O)PR1R2. To the best of our knowledge, this is the first example of nickel-catalyzed C-P coupling of aryl mesylates and tosylates. Most of the substrates gave moderate to good yields under our catalytic system.

A general palladium catalyst system for suzuki-miyaura coupling of potassium aryltrifluoroborates and aryl mesylates

(Figure presented) The first general examples of palladium-catalyzed Suzuki-type cross-coupling of aryl and heteroaryl mesylates with potassium aryl and heteroaryltrifluoroborates are presented. In addition to biaryl couplings, the cross-coupling reactions of aryl mesylates with alkyl and vinyltrifluoroborate salts have also been successfully accomplished.