21150-15-2Relevant articles and documents
Evidence of an nN(amide) → π*ArInteraction in N-Alkyl- N, N′-diacylhydrazines
Deka, Jugal Kishore Rai,Sahariah, Biswajit,Sakpal, Sushil S.,Bar, Arun Kumar,Bagchi, Sayan,Sarma, Bani Kanta
supporting information, p. 7003 - 7007 (2021/05/26)
1,2-Dibenzoyl-1-tert-butylhydrazine (RH-5849) and related N-alkyl-N,N′-diacylhydrazines are environmentally benign insect growth regulators. Herein, we show that an unusual nN(amide) → π*Ar interaction mediated by a hydrazide amide nitrogen atom plays a crucial role in stabilizing their biologically active trans-cis (t-c) rotameric conformations. We provide NMR and IR spectroscopic evidence for the presence of these interactions, which is also supported by X-ray crystallographic and computational studies.
Synthesis of 3-methyl-[1,2,4]-triazepino[6,5,4-jk]carbazol-4(3H)one
Peet,Sunder
, p. 1147 - 1150 (2007/10/05)
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