21259-20-1 Usage
Description
T-2 Toxin is a potent trichothecene mycotoxin produced by the genus Fusarium fungi, which can be found in feedstuffs, cereal grains, and Fusarium-infected wheat, barley, and rice crops. It is a white powder that has the ability to bind to and inhibit peptidyltransferase in the 60S ribosomal subunit, inducing a ribotoxic stress response that triggers JNK and p38 MAPK signaling. T-2 Toxin is known for its cytotoxic effects on primary pig alveolar macrophages (PAMs) and its ability to induce DNA damage and cell death on prolonged administration.
Uses
1. Used in Research and Development:
T-2 Toxin is used as a research tool for studying the effects of mycotoxins on cellular processes, immune responses, and the development of potential countermeasures against their toxic effects. Its ability to induce DNA damage, cell death, and modulate immune responses makes it a valuable compound for understanding the mechanisms of mycotoxin-induced toxicity and developing strategies to mitigate their impact.
2. Used in Agricultural and Food Safety:
T-2 Toxin is used as a reference material for the development and validation of analytical methods and detection techniques to monitor and control the presence of mycotoxins in agricultural products and the food supply chain. This helps ensure the safety and quality of food products, protecting consumers from the potential health risks associated with mycotoxin contamination.
3. Used in Pharmaceutical and Biomedical Applications:
T-2 Toxin can be used as a starting point for the development of new drugs or therapies targeting specific cellular processes and signaling pathways affected by the toxin. Its ability to induce cell death and modulate immune responses may provide insights into the development of novel treatments for various diseases and conditions.
4. Used in Environmental and Ecotoxicological Studies:
T-2 Toxin can be employed in environmental and ecotoxicological research to assess the impact of mycotoxins on ecosystems, wildlife, and the environment. This can help in understanding the ecological consequences of mycotoxin contamination and inform strategies for environmental protection and remediation.
5. Used in Educational and Training Programs:
T-2 Toxin can be utilized as a teaching aid in educational and training programs related to mycotoxins, their effects on human and animal health, and the importance of food safety and quality. This can help raise awareness and improve knowledge and skills in the detection, prevention, and management of mycotoxin contamination in the food supply chain.
Safety Profile
Poison by ingestion,
intramuscular, subcutaneous, intraperitoneal,
intracerebral, and intravenous routes.
Moderately toxic by inhalation.
Experimental teratogenic and reproductive
effects. A skin irritant. Questionable
carcinogen with experimental neoplastigenic
data. Mutation data reported. When heated
to decomposition it emits acrid smoke and
irritating fumes.
Check Digit Verification of cas no
The CAS Registry Mumber 21259-20-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,2,5 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21259-20:
(7*2)+(6*1)+(5*2)+(4*5)+(3*9)+(2*2)+(1*0)=81
81 % 10 = 1
So 21259-20-1 is a valid CAS Registry Number.
InChI:InChI=1/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24-/m0/s1
