2131-60-4 Usage
Description
4-HYDROXYPHENYLISOTHIOCYANATE, also known as 4-Isothiocyanatophenol, is an organic compound with the chemical formula C7H5NS. It is characterized by its isothiocyanate functional group, which provides it with unique chemical properties and reactivity. 4-HYDROXYPHENYLISOTHIOCYANATE is known for its potential applications in various fields due to its ability to form fluorescent probes and its reactivity with biologically relevant compounds.
Uses
Used in Chemical Synthesis:
4-HYDROXYPHENYLISOTHIOCYANATE is used as a key intermediate in the synthesis of various organic compounds, particularly those with potential applications in the field of biochemistry and molecular biology. Its isothiocyanate group allows for the formation of stable conjugates with biological molecules, making it a valuable building block for the development of new compounds.
Used in Fluorescent Probe Development:
In the field of biochemistry and molecular biology, 4-HYDROXYPHENYLISOTHIOCYANATE is used as a precursor for the development of fluorescent probes. These probes are essential tools for studying the structure, function, and interactions of biologically relevant compounds. The compound's ability to form stable conjugates with biomolecules makes it an ideal candidate for the creation of probes that can be used to track and visualize specific biological processes.
Used in the Synthesis of Tricarbocyanine Dyes:
4-HYDROXYPHENYLISOTHIOCYANATE is used as a starting material in the synthesis of 3 functionalized tricarbocyanine dyes. These dyes have potential applications as fluorescent probes for biologically pertinent compounds, allowing researchers to study various biological processes with greater precision and detail.
Check Digit Verification of cas no
The CAS Registry Mumber 2131-60-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,3 and 1 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2131-60:
(6*2)+(5*1)+(4*3)+(3*1)+(2*6)+(1*0)=44
44 % 10 = 4
So 2131-60-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H5NOS/c9-7-3-1-6(2-4-7)8-5-10/h1-4,9H
2131-60-4Relevant articles and documents
First Examples of H2S-Releasing Glycoconjugates: Stereoselective Synthesis and Anticancer Activities
Fortunato, Serena,Lenzi, Chiara,Granchi, Carlotta,Citi, Valentina,Martelli, Alma,Calderone, Vincenzo,Di Pietro, Sebastiano,Signore, Giovanni,Di Bussolo, Valeria,Minutolo, Filippo
, p. 614 - 620 (2019)
H2S donors are currently emerging as promising therapeutic agents in a wide variety of pathologies, including tumors. Cancer cells are characterized by an enhanced uptake of sugars, such as glucose. Therefore, novel glycoconjugated H2/sub
4-Dimethylaminopyridine-catalyzed synthesis of isothiocyanates from amines and carbon disulfide
Rong, Hao-Jie,Chen, Tao,Xu, Ze-Gang,Su, Tian-Duo,Shang, Yu,Wang, Yong-Qiang,Yang, Cui-Feng
, (2021/03/03)
Isothiocyanates were synthesized by reactions between primary amines and CS2 in the presence of 4-dimethylaminopyridine as a catalyst and tert-butyl hydroperoxide as an oxidant. Various aryl, benzyl, alkyl, and hydroxyl amines were transformed into the corresponding isothiocyanates in 41–82% yields.
Direct, Microwave-Assisted Synthesis of Isothiocyanates
Janczewski, ?ukasz,Gajda, Anna,Gajda, Tadeusz
supporting information, p. 2528 - 2532 (2019/04/03)
A microwave-assisted desulfuration of readily available dithiocarbamates, formed in situ from primary amines, leading to target isothiocyanates has been developed. This efficient protocol provides a rapid, environmentally benign route to aliphatic and aromatic isothiocyanates.
