2160-52-3

Basic information

• Product Name: ethyl 5-bromo-4-nitrothiophene-2-carboxylate
• Synonyms: ethyl 5-bromo-4-nitrothiophene-2-carboxylate;2-thiophenecarboxylic acid, 5-bromo-4-nitro-, ethyl ester;5-bromo-4-nitro-2-thiophenecarboxylic acid ethyl ester;5-bromo-4-nitro-thiophene-2-carboxylic acid ethyl ester
• CAS NO: 2160-52-3
• Molecular Formula: C₇H₆BrNO₄S
• Molecular Weight: 280.09584
• Mol File: 2160-52-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: ethyl 5-bromo-4-nitrothiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-bromo-4-nitrothiophene-2-carboxylate(2160-52-3)
• EPA Substance Registry System: ethyl 5-bromo-4-nitrothiophene-2-carboxylate(2160-52-3)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 2160-52-3(Hazardous Substances Data)

Usage

General Description

Ethyl 5-bromo-4-nitrothiophene-2-carboxylate is a chemical compound with the molecular formula C8H6BrNO4S and a molecular weight of 274.10 g/mol. It is a yellow crystalline solid that is primarily used in the pharmaceutical industry for the synthesis of various important compounds. ethyl 5-bromo-4-nitrothiophene-2-carboxylate is known for its ability to act as a versatile building block in the production of biologically active substances and pharmaceuticals. It is also used in the field of organic chemistry as a reagent in the synthesis of novel molecules with potential medicinal properties. Additionally, this chemical is utilized in various research and development applications for the creation of new drug candidates and molecular probes.

Upstream product

• 5751-83-7 ethyl 5-bromothiophene-2-carboxylate 

Relevant articles and documents

Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides

The discovery of a novel class of HCV NS5B polymerase inhibitors, 3-arylsulfonylamino-5-phenyl-thiophene-2-carboxylic acids is described. SAR studies have yielded several potent inhibitors of HCV polymerase as well as of HCV subgenomic RNA replication in

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1 -phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof.