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216311-09-0

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216311-09-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 216311-09-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,6,3,1 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 216311-09:
(8*2)+(7*1)+(6*6)+(5*3)+(4*1)+(3*1)+(2*0)+(1*9)=90
90 % 10 = 0
So 216311-09-0 is a valid CAS Registry Number.

216311-09-0Relevant articles and documents

Discovery of 1-(β-amino substituted-β-alanyl)-N,N- dimethylindoline-2-carboxamides as novel nonpeptide antagonists of nociceptin/orphanin FQ receptor: Efficient design, synthesis, and structure-activity relationship studies

Hayashi, Shigeo,Ohashi, Katsuyo,Nakata, Eriko,Emoto, Chie

, p. 228 - 242 (2012/11/07)

Since the discovery of endogenous nociceptin/orphanin FQ (N/OFQ) peptide and N/OFQ peptide (NOP) receptor [or opioid-receptor-like-1 (ORL1) receptor], the structures, distribution, and pharmacology have been reported in detail. N/OFQ and NOP receptor are

5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines

-

, (2008/06/13)

This invention is directed to dihydropyrimidine compounds of the following formula: which are selective antagonists for human α1Areceptors. This invention is also related to uses of these compounds for lowering intraocular pressure, inhibiting cholesterol synthesis, relaxing lower urinary tract tissue, the treatment of benign prostatic hyperplasia, impotency, cardiac arrhythmia and for the treatment of any disease where antagonism of the α1Areceptor may be useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-defined compounds and a pharmaceutically acceptable carrier.

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