30897-90-6 Usage
Description
4-Fluoro-2-methylphenylmagnesium bromide is an organometallic compound that consists of a magnesium atom bonded to a 4-fluoro-2-methylphenyl group and a bromide ion. It is a versatile reagent in organic chemistry, known for its unique properties and reactivity.
Uses
Used in Organic Synthesis:
4-Fluoro-2-methylphenylmagnesium bromide is used as a reagent for the synthesis of various organic compounds. Its application is due to its ability to participate in a range of reactions, such as cross-coupling and Grignard reactions, which facilitate the formation of carbon-carbon and carbon-heteroatom bonds.
Used in Pharmaceutical Industry:
4-Fluoro-2-methylphenylmagnesium bromide is used as an intermediate for the production of pharmaceuticals. Its application is attributed to its role in the synthesis of complex organic molecules, which can be further modified to create new drugs with specific therapeutic properties.
Used in Agrochemicals:
4-Fluoro-2-methylphenylmagnesium bromide is used as a building block for the development of agrochemicals. Its application is due to its ability to form the core structures of various agrochemicals, such as pesticides and herbicides, which are essential for crop protection and increased agricultural productivity.
Used in Dyestuffs:
4-Fluoro-2-methylphenylmagnesium bromide is used as a precursor in the synthesis of dyestuffs. Its application is based on its potential to form chromophores and other functional groups that impart color and other properties to dyes, which are used in various industries, such as textiles and printing.
Check Digit Verification of cas no
The CAS Registry Mumber 30897-90-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,8,9 and 7 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 30897-90:
(7*3)+(6*0)+(5*8)+(4*9)+(3*7)+(2*9)+(1*0)=136
136 % 10 = 6
So 30897-90-6 is a valid CAS Registry Number.
InChI:InChI=1/C7H6F.BrH.Mg/c1-6-3-2-4-7(8)5-6;;/h2,4-5H,1H3;1H;/q-1;;+2/p-1
30897-90-6Relevant articles and documents
6-OXO-1,6-DIHYDROPYRIDAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
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Paragraph 0145-0146; 0201-0202, (2021/11/14)
A 6-oxo-1,6-dihydropyridazine derivative, a preparation method therefor and medical use thereof, in particular, a 6-oxo-1,6-dihydropyridazine derivative represented by general formula (I), a preparation method therefor, and a pharmaceutical composition containing the derivative, and use thereof as a NaV inhibitor and use thereof in the preparation of a drug for the treatment and/or prevention of pain and pain-related diseases. Each substituent in general formula (I) is the same as defined in the description.
Synthesis of the NK1 receptor antagonist GW597599. Part 1: development of a scalable route to a key chirally pure arylpiperazine
Guercio, Giuseppe,Bacchi, Sergio,Goodyear, Michael,Carangio, Antonella,Tinazzi, Francesco,Curti, Stefano
, p. 1188 - 1194 (2013/01/03)
GW5975991 is a novel NK-1 antagonist currently under investigation for the treatment of CNS disorders and emesis. The initial synthetic route devised from the medicinal chemistry one, used several hazardous reagents, gave low yields, and produced high lev