21759-74-0

Basic information

• Product Name: 2-Butenoic acid, 3-[(phenylmethyl)amino]-, ethyl ester, (2Z)-
• CAS NO: 21759-74-0
• Molecular Formula: C13H17NO2
• Molecular Weight: 219.283
• Mol File: 21759-74-0.mol
• Article Data: 47

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 3-[(phenylmethyl)amino]-, ethyl ester, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 3-[(phenylmethyl)amino]-, ethyl ester, (2Z)-(21759-74-0)
• EPA Substance Registry System: 2-Butenoic acid, 3-[(phenylmethyl)amino]-, ethyl ester, (2Z)-(21759-74-0)

Safety Data

• Hazardous Substances Data: 21759-74-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 626-34-6 ethyl 3-aminobut-2-enoate 
• 623-70-1 ethyl (E)-crotonate 
• 141-97-9 ethyl acetoacetate 
• 100-46-9 benzylamine 
• 609-11-0 ethyl 2,3-dibromobutyrate 
• 21731-13-5 (E)-3-Benzylamino-but-2-enoic acid ethyl ester 

Downstream Products

• 103910-18-5 4-(3-benzylamino-2-ethoxycarbonyl-2-butenylidene)-2-phenyl-5-oxazolone 
• 103910-17-4 3-benzamido-1-benzyl-5-ethoxycarbonyl-6-methyl-2(1H)-pyridone 
• 66439-03-0 diethyl 1-benzyl-1,4-dihydro-2,6-dimethyl-4-phenylpyridine-3,5-dicarboxylate 
• 146763-31-7 1-Benzyl-4-(4-chloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 30131-53-4 1-Benzyl-2,6-dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 72284-55-0 1-Benzyl-2,6-dimethyl-4-(3-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 74979-66-1 1-Benzyl-4-(4-methoxy-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 6343-54-0 N-benzylformamide 
• 74328-26-0 (E)-3-{[1-Phenyl-meth-(E)-ylidene]-amino}-but-2-enal 
• 6335-80-4 ethyl 3-(benzylamino)butanoate 
• 121006-14-2 3-(Benzylamino)-1-butanol 
• 58412-48-9 diethyl 1-benzyl-2,5-dimethyl-1H-pyrrole-3,4-dicarboxylate 
• 38468-75-6 1-benzyl-4-hydroxy-6-methyl-3-phenyl-1H-pyridin-2-one 
• 138485-57-1 1-Benzyl-4-hydroxy-2-methyl-6-oxo-5-phenyl-1,6-dihydro-pyridine-3-carboxylic acid 

Relevant articles and documents

Carbonylation of silylated hydroxymethyl aziridines to β-lactams

Functionalized β-lactams are synthesized by carbonylative ring expansion of silylated hydroxymethyl aziridines catalyzed by dicobalt octacarbonyl, a process that proceeds with inversion of configuration. Ring opening and elimination occurs on attempted carbonylation of aziridine carboxylates.

Highly efficient and facile synthesis of β-enaminones catalyzed by diphenylammonium triflate

Abstract: The catalytic performance of diphenylammonium triflates as an organocatalyst in the synthesis of β-enaminones from various substituted β-diketones and amides (or amines) were evaluated. A wide range of β-enaminones were efficiently synthesized in good to excellent yields under mild reaction conditions. Applying diphenylammonium triflate (DPAT) as catalyst makes this protocol cost-effective, low corrosive and easy to handle. Graphic abstract: [Figure not available: see fulltext.].

Transformation of One-Dimensional Achiral Structure to Three-Dimensional Chiral Structure: Mechanistic Study and Catalytic Activities of Chiral Structure

We have isolated two copper-based coordination polymers through solvent diffusion and solvothermal methods using copper salt, furan dicarboxylic acid (FDC), 4,4′-bipyridine (bpy) in MeOH/ethylene glycol, and water solvents. Compound 1 is adopting P21/c space group and adopts a one-dimensional wirelike structure with a free carboxylate anion. Compound 2 crystallizes in chiral space group P65. This is a three-dimensional structure with helical chains. This helicity might be the reason for chiral generation and symmetry breaking. We have converted compound 1 to compound 2 using grinding, followed by a solvothermal method. The circular dichroism data of 2 showed that it is an enantioenriched compound. We have shown that compound 2 is a very good catalyst for chemo- and regioselective enamination reaction and for azide-alkyne Huisgen cycloaddition, respectively.