21763-04-2

Basic information

• Product Name: 2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI)
• Synonyms: 2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI);neoflavan
• CAS NO: 21763-04-2
• Molecular Formula: C₁₅H₁₄O
• Molecular Weight: 210.27106
• Product Categories: PHENYL
• Mol File: 21763-04-2.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 312.5°C at 760 mmHg
• Flash Point: 138.5°C
• Appearance: /
• Density: 1.098g/cm³
• Vapor Pressure: 0.000968mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI)(21763-04-2)
• EPA Substance Registry System: 2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI)(21763-04-2)

Safety Data

• Hazardous Substances Data: 21763-04-2(Hazardous Substances Data)

Usage

Description

2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI), also known as the simplest member of the neoflavan class, is a chemical compound characterized by a 3,4-dihydro-2H-1-benzopyran structure with a phenyl group substitution at position 4. 2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI) holds potential applications in various industries due to its unique chemical properties.

Uses

Used in Pharmaceutical Industry:
2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI) is used as a pharmaceutical compound for its potential therapeutic effects. The compound's unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs and therapies.
Used in Chemical Research:
In the field of chemical research, 2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI) serves as a valuable compound for studying the properties and behavior of neoflavans. This understanding can lead to the discovery of new applications and the development of novel compounds with improved characteristics.
Used in Material Science:
2H-1-Benzopyran,3,4-dihydro-4-phenyl-(9CI) may also find applications in material science, where its unique chemical structure could be utilized to create new materials with specific properties. These materials could have potential uses in various industries, such as electronics, automotive, or aerospace.
Used in Cosmetics Industry:
The compound's potential applications extend to the cosmetics industry, where it could be used as an active ingredient in skincare or hair care products. Its unique properties may contribute to improved product performance, such as enhanced antioxidant or anti-inflammatory effects.

InChI:InChI=1/C15H14O/c1-2-6-12(7-3-1)13-10-11-16-15-9-5-4-8-14(13)15/h1-9,13H,10-11H2

Upstream product

• 93622-12-9 N'-(chroman-4-ylidene)-4-methylbenzenesulfonohydrazide 
• 98-80-6 phenylboronic acid 
• 1017394-99-8 5-phenyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine 
• 61198-52-5 3,4-dihydro-4-phenyl-2H-1-benzopyran-2-one 
• 589-10-6 phenoxyethyl bromide 
• 108-95-2 phenol 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 54705-26-9 ortho-[(N-methyl)carbamoyl]phenyl benzyl sulfoxide 
• 100-39-0 benzyl bromide 
• 1531-80-2 2-(benzylthio)benzoic acid 
• 54705-19-0 2-(benzylthio)-N-methylbenzamide 
• 93021-93-3 1-methoxy-4-((3-phenylprop-2-yn-1-yl)oxy)benzene 
• 92496-20-3 (3-phenoxyprop-1-yn-1‐yl)benzene 
• 51870-64-5 4-phenyl-2H-benzo[b]pyran 

Downstream Products

• 25173-82-4 (2-hydroxy-phenyl)-phenyl-acetic acid 
• 61986-73-0 2-(1-phenylpropyl)phenol 

Relevant articles and documents

N-Atom Deletion in Nitrogen Heterocycles

Excising the nitrogen in secondary amines, and coupling the two residual fragments is a skeletal editing strategy that can be used to construct molecules with new skeletons, but which has been largely unexplored. Here we report a versatile method of N-atom excision from N-heterocycles. The process uses readily available N-heterocycles as substrates, and proceeds by N-sulfonylazidonation followed by the rearrangement of sulfamoyl azide intermediates, providing various cyclic products. Examples are provided of deletion of nitrogen from natural products, synthesis of chiral O-heterocycles from commercially available chiral β-amino alcohols, formal inert C?H functionalization through a sequence of N-directed C?H functionalization and N-atom deletion reactions in which the N-atom can serve as a traceless directing group.

PROCESS FOR THE PRODUCTION OF 4-SUBSTITUTED CHROMANES VIA GOLD CATALYSIS

Disclosed herein is single step process for the synthesis of 4-aryl substituted chromanes of compound of formula 2 comprising subjecting 3-aryloxy-1-phenylpropan-1-ol of formula 1 to gold(III) chloride-catalyzed intramolecular Friedel-Crafts reaction to obtain 4-aryl substituted chromanes. The invention further discloses novel 4-substituted Chromane compounds.

Synthesis of 1-aryl-tetralins and 4-aryl-benzopyrans by sulfoxide-mediated benzylic carbocation cyclizations

An alkylation/cyclization sequence, with both steps mediated by the ortho-N-methylformamido-phenylsulfinyl function, provided two new C-C bonds and an efficient entry to 1-aryl-tetralins and 4-aryl-benzopyrans. Scope and limits of the process have been studied in detail.