21770-81-0 Usage
Description
1-Methylguanidine hydrochloride is an organic compound with the chemical formula C7H16ClN5. It is a white solid and is known for its inhibitory action against trypsin catalysis. 1-Methylguanidine hydrochloride has been found to inhibit the metabolism of certain hepatic drugs that are mediated by cytochrome P450 protein in human liver microsome and hepatocyte.
Uses
Used in Pharmaceutical Industry:
1-Methylguanidine hydrochloride is used as an inhibitor for trypsin catalysis, which plays a crucial role in the pharmaceutical industry. Its ability to inhibit the metabolism of certain hepatic drugs can be beneficial in the development of new drugs and therapies.
Used in Chemical Synthesis:
1-Methylguanidine hydrochloride is used as a starting material or intermediate in the synthesis of various compounds. It is used to prepare biaryl derivatives, which act as BACE1 inhibitors, a target for the treatment of Alzheimer's disease. Additionally, it is used in the synthesis of modified xylose, which is utilized in the production of biodegradable composite hydrogels.
Used in Energy Storage:
1-Methylguanidine hydrochloride is used in the preparation of methylguanidinium borohydride ionic liquid, which is applicable as a hydrogen storage material. This application is significant in the field of energy storage and renewable energy, as it contributes to the development of more efficient and sustainable energy solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 21770-81-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,7,7 and 0 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 21770-81:
(7*2)+(6*1)+(5*7)+(4*7)+(3*0)+(2*8)+(1*1)=100
100 % 10 = 0
So 21770-81-0 is a valid CAS Registry Number.
InChI:InChI=1/C2H7N3.ClH/c1-2(3)5-4;/h5H,1,3-4H2;1H
21770-81-0Relevant articles and documents
PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS
-
, (2010/03/02)
The invention relates to a process for straightening keratin fibres, comprising: (i) a step in which a straightening composition containing at least two denaturing agents is applied to the keratin fibres, (ii) a step in which the temperature of the keratin fibres is raised, using a heating means, to a temperature of between 110 and 250° C.
SIMPLE AMIDINIUM CARBOXYLATES - AN MO TREATMENT OF MOLECULAR GEOMETRY AND ELECTRONIC STRUCTURE
Krechl, Jiri,Boehm, Stanislav,Smrckova, Svatava,Kuthan, Josef
, p. 673 - 683 (2007/10/02)
Carboxylates of amidines (I,II), substituted guanidine (III) and iso(thio)ureas (IV,V) were prepared.Nonempirical quantum chemical treatment of the electronic structure of simple compounds I-V, based on total molecular geometry optimization, their preparation and physicochemical data are reported.Interaction between the two amidinium nitrogens and carboxylate oxygens is mediated by hydrogen bonds and alternation of charge distribution.
