218628-44-5

Basic information

• Product Name: Ethyl 2-(3,4-methylenedioxyphenyl)-2-(phenylthio)acetate
• Synonyms: Ethyl 2-(3,4-methylenedioxyphenyl)-2-(phenylthio)acetate
• CAS NO: 218628-44-5
• Molecular Weight: 316.378
• Mol File: 218628-44-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethyl 2-(3,4-methylenedioxyphenyl)-2-(phenylthio)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-(3,4-methylenedioxyphenyl)-2-(phenylthio)acetate(218628-44-5)
• EPA Substance Registry System: Ethyl 2-(3,4-methylenedioxyphenyl)-2-(phenylthio)acetate(218628-44-5)

Safety Data

• Hazardous Substances Data: 218628-44-5(Hazardous Substances Data)

Upstream product

• 274-09-9 Methylenedioxybenzene 
• 7605-25-6 ethyl phenylsulfenylacetate 
• 60178-25-8 ethyl α-chloro-α-(phenylthio)acetate 

Downstream Products

• 250261-59-7 N-(Cyclohex-2-enyl)-N-(4-methoxybenzyl)-2-(3,4-methylenedioxyphenyl)-2-(phenylthio)acetamide 
• 951327-62-1 C₂₃H₂₅NO₅ 
• 951327-61-0 C₂₇H₃₃NO₇ 
• 951327-60-9 C₂₇H₃₁NO₈ 
• 951327-58-5 C₃₃H₃₆ClNO₈S 
• 951327-57-4 C₃₃H₃₆BrNO₈S 
• 218628-45-6 2-(3,4-Methylenedioxyphenyl)-2-(phenylthio)acetic acid 

Relevant articles and documents

Chemoenzymatic approaches to the montanine alkaloids: A total synthesis of (+)-brunsvigine

The readily available and enzymatically derived cis-1,2-dihydrocatechols 3a and 3b have been elaborated over 17 steps, including a novel radical addition/elimination sequence, into the enantiomer, (+)-1, of the montanine alkaloid brunsvigine [(-)-1].

Formal synthesis of (±)-pancracine using stereoselective radical cyclization of N-(2-cyclohexenyl)-α-aryl-α-(phenylthio)acetamide

(Me3Si)3SiH-mediated 5-exo-trig radical cyclization of N-(2-cyclohexcnyl)-α-aryl-α-(phenylthio)acetamide 19 proceeded in a stereoselective manner to give (3R*,3aS*,7aS*)-3-aryloctahydroindol-2-one 20. The product was transformed into the key intermediate 25 for the synthesis of (±)-pancracine (1), a montanine-type Amaryllidaceae alkaloid.