21921-70-0 Usage
Description
6-chloro-1H-quinolin-4-one is a quinoline derivative with the molecular formula C9H6ClNO. It is a chemical compound that features a chloro substituent on the quinoline ring, which endows it with unique properties and reactivity. 6-chloro-1H-quinolin-4-one has garnered interest due to its potential applications in various fields, including pharmaceuticals, agrochemicals, and material science, as well as its biological activities.
Uses
Used in Pharmaceutical and Agrochemical Industries:
6-chloro-1H-quinolin-4-one is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure allows it to be a key component in the development of new drugs and pesticides, contributing to advancements in healthcare and agriculture.
Used in Material Science:
6-chloro-1H-quinolin-4-one has been investigated for its potential use as a precursor in the development of novel materials and organic compounds. Its reactivity and structural features make it a promising candidate for creating innovative materials with specific properties for various applications.
Used in Medicinal Chemistry Research:
6-chloro-1H-quinolin-4-one has been studied for its biological activities, particularly its potential as an antibacterial and antifungal agent. This research is crucial for the discovery of new treatments and therapies to combat resistant infections and contribute to the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 21921-70-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,2 and 1 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 21921-70:
(7*2)+(6*1)+(5*9)+(4*2)+(3*1)+(2*7)+(1*0)=90
90 % 10 = 0
So 21921-70-0 is a valid CAS Registry Number.
21921-70-0Relevant articles and documents
Structural optimization of quinolon-4(1 H)-imines as dual-stage antimalarials: Toward increased potency and metabolic stability
Ressurrei??o, Ana S.,Gon?alves, Daniel,Sitoe, Ana R.,Albuquerque, Ine?s S.,Gut, Jiri,Góis, Ana,Gon?alves, Lídia M.,Bronze, Maria R.,Hanscheid, Thomas,Biagini, Giancarlo A.,Rosenthal, Philip J.,Prude?ncio, Miguel,O'Neill, Paul,Mota, Maria M.,Lopes, Francisca,Moreira, Rui
, p. 7679 - 7690 (2013)
Discovery of novel effective and safe antimalarials has been traditionally focused on targeting erythrocytic parasite stages that cause clinical symptoms. However, elimination of malaria parasites from the human population will be facilitated by intervent
Direct C-3-alkenylation of quinolones via palladium-catalyzed C-H functionalization
Li, Mingzong,Li, Liangxi,Ge, Haibo
supporting information; experimental part, p. 2445 - 2449 (2010/12/25)
An unprecedented C-3-alkenylation of quinolones was reported through palladium-catalyzed C-H functionalization with 1% catalyst loading. This method provides an efficient route to a variety of new quinolone derivatives.
Use of polyphosphoric acid in the hydrolysis of chromone esters
He, Xungui,Li, Zhiyu,You, Qidong
, p. 709 - 714 (2007/10/03)
Hydrolysis of esters was achieved in fairly high yield (59-98%) using polyphosphoric acid (PPA). The reagent was particularly useful for the hydrolysis of chromone side chain esters without ring opening.