2205-78-9 Usage
Description
19-Nor-17-alpha-pregna-3,5-dien-20-yne-3,17-diol, diacetate is a chemical compound derived from the pregnane family, characterized by its unique molecular structure and off-white solid appearance. It possesses a 3,5-dien-20-yne backbone with a 17-diol substitution and diacetate functional groups, which contribute to its chemical properties and potential applications.
Uses
Used in Pharmaceutical Industry:
19-Nor-17-alpha-pregna-3,5-dien-20-yne-3,17-diol, diacetate is used as a pharmaceutical compound for its estrogenic activity. It is particularly effective in inhibiting the development of the uterus decidua, making it a potential candidate for hormone-related treatments and therapies.
Used in Research and Development:
In the field of research and development, 19-Nor-17-alpha-pregna-3,5-dien-20-yne-3,17-diol, diacetate serves as a valuable compound for studying the effects of steroidal structures on biological systems. Its unique molecular composition allows scientists to explore its potential applications in various areas, including endocrinology, reproductive health, and drug development.
Used in Hormone Replacement Therapy:
Due to its estrogenic activity, 19-Nor-17-alpha-pregna-3,5-dien-20-yne-3,17-diol, diacetate may be used as a component in hormone replacement therapy, particularly for conditions related to hormonal imbalances or menopausal symptoms. Its ability to inhibit the development of the uterus decidua could provide targeted treatment options for specific patient populations.
Used in Contraceptive Development:
The compound's impact on the uterus decidua also makes it a potential candidate for contraceptive development. By understanding its mechanism of action and optimizing its delivery, it could be incorporated into contraceptive products to provide effective birth control options for women.
Used in Veterinary Medicine:
In veterinary medicine, 19-Nor-17-alpha-pregna-3,5-dien-20-yne-3,17-diol, diacetate may be utilized for similar applications as in human medicine, such as hormone-related treatments, reproductive health management, and contraceptive development. Its potential use in this industry could provide valuable tools for managing the health and well-being of various animal species.
Check Digit Verification of cas no
The CAS Registry Mumber 2205-78-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,0 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2205-78:
(6*2)+(5*2)+(4*0)+(3*5)+(2*7)+(1*8)=59
59 % 10 = 9
So 2205-78-9 is a valid CAS Registry Number.
InChI:InChI=1/C24H30O4/c1-5-24(28-16(3)26)13-11-22-21-8-6-17-14-18(27-15(2)25)7-9-19(17)20(21)10-12-23(22,24)4/h1,6,14,19-22H,7-13H2,2-4H3/t19-,20+,21+,22-,23-,24-/m0/s1
2205-78-9Relevant articles and documents
Synthetic method of tibolone
-
, (2020/05/01)
The intention relates to a synthesis method of tibolone, which specifically comprises the following steps: 1) ethynylation reaction: introducing acetylene gas into an acidic decarboxylate (I) toluenesolution as a raw material, and reacting to obtain norethindrone (II); 2) acylation reaction: adding acetic anhydride and an acid-binding agent into the norethindrone (II) obtained in the step 1), controlling the room temperature, dropwise adding acetyl chloride, and stirring to react for 6 hours until the raw material is completely reacted to obtain an acylate (III); 3) carrying out debrominationreaction on the acylate to obtain 4, 6-diene norethindrone acetate (V); 4) methylation reaction: adding an ether solvent into the 4, 6-diene norethindrone acetate (V), cooling to -10 to 30 DEG C, dropwisely adding a methylation reagent, controlling the temperature at 0-5 DEG C, and stirring to react until the raw material reaction is complete, thereby obtaining 7alpha-methyl norethindrone acetate(VI); 5) transposition reaction: reacting the 7 alpha- methyl norethindrone acetate (VI) to obtain a transposition substance (VII) wet product, and 6) hydrolysis reaction: reacting the transpositionsubstance (VII) to obtain the tibolone.
Synthesis of 13-alkyl-gon-4-ones
-
, (2008/06/13)
The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.
