22241-18-5

Basic information

• Product Name: Benzaldehyde, 3-hydroxy-, oxime (9CI)
• Synonyms: Benzaldehyde, 3-hydroxy-, oxime (9CI)
• CAS NO: 22241-18-5
• Molecular Formula: C₇H₇NO₂
• Molecular Weight: 137.13598
• Product Categories: OXIME
• Mol File: 22241-18-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 293.0±23.0 °C(Predicted)
• Appearance: /
• Density: 1.18±0.1 g/cm3(Predicted)
• PKA: 9.46±0.10(Predicted)
• CAS DataBase Reference: Benzaldehyde, 3-hydroxy-, oxime (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3-hydroxy-, oxime (9CI)(22241-18-5)
• EPA Substance Registry System: Benzaldehyde, 3-hydroxy-, oxime (9CI)(22241-18-5)

Safety Data

• Hazardous Substances Data: 22241-18-5(Hazardous Substances Data)

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 

Downstream Products

• 100-83-4 meta-hydroxybenzaldehyde 
• 618-49-5 3-hydroxybenzamide 
• 27559-45-1 3-hydroxy-N-phenyl-benzamide 
• 96859-34-6 5-(3-hydroxyphenyl)-1H-tetrazole 
• 596095-24-8 C₇H₆ClNO₂ 
• 89937-61-1 N-(3'-hydroxybenzyl)hydroxylamine 
• 55682-11-6 3-cyanophenyl acetate 
• 873-62-1 m-cyanophenol 

Relevant articles and documents

2-(3-Hydroxybenzyl)benzo[d]isothiazol-3(2H)-one Mannich base derivatives as potential multifunctional anti-Alzheimer’s agents

A series of 2-(3-hydroxybenzyl)benzo[d]isothiazol-3(2H)-one Mannich base derivatives were designed as potential multifunctional agents against Alzheimer’s disease. The twelve derivatives were synthesized and evaluated with various biological activities. I

Cu(II)–metformin immobilized on graphene oxide: an efficient and recyclable catalyst for the Beckmann rearrangement

Abstract: In this study, for the first time, the copper(II) nanoparticles (NPs) have been immobilized on metformin-functionalized graphene oxide and then its catalytic applications have been investigated in synthesis of amides from aldoximes (Beckmann rearrangement). The chemical structure of prepared catalyst has been characterized by various analyses like FT-IR, TGA, TEM, SEM, EDX, and ICP. All analyses confirm the successful and stable immobilization of copper NPs on functionalized graphene oxide. This synthesized heterogeneous nanocatalyst showed excellent catalytic activity with high product yields and short reaction times. Also, the suggested catalyst could be recycled ten times without a drastic decrease in its catalytic activity. Graphic abstract: [Figure not available: see fulltext.].

Synthesis and cytotoxic evaluation of undecenoic acid-based oxime esters

A series of undecenoic acid-based aldoxime esters have been synthesized using various substituted benzaldehydes and undecenoic acid. These oxime esters have been evaluated for their cytotoxic activities against HeLa, B16-F10, SKOV3, MCF7 and CHO-K1 normal cell line using MTT assay. Most of the synthesized compounds exhibit cytotoxicity. Particularly, 2,3-dimethoxy (IC50 value 12.48μM) and 3-methoxy (IC50 value 13.58μM) derivatives exhibit promising activities against SKOV3 cell lines. All the synthesized compounds are non-toxic towards the Chinese hamster ovary (CHO-K1) normal cell line.