55682-11-6

Basic information

• Product Name: (3-cyanophenyl) acetate
• Synonyms: (3-cyanophenyl) acetate;1-Acetoxy-3-cyanobenzene;1-Cyano-3-acetoxybenzene;3-Acetoxybenzonitrile;HSNBGFVFXQYLMI-UHFFFAOYSA-N
• CAS NO: 55682-11-6
• Molecular Formula: C₉H₇NO₂
• Molecular Weight: 161.16
• Mol File: 55682-11-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 266.1°Cat760mmHg
• Flash Point: 119.4°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 0.00881mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: (3-cyanophenyl) acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (3-cyanophenyl) acetate(55682-11-6)
• EPA Substance Registry System: (3-cyanophenyl) acetate(55682-11-6)

Safety Data

• Hazardous Substances Data: 55682-11-6(Hazardous Substances Data)

Usage

General Description

(3-cyanophenyl) acetate is a chemical compound with the molecular formula C10H7NO2. It is a white solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used as a building block in the preparation of various organic compounds. (3-cyanophenyl) acetate is known for its diverse range of applications in the fields of chemistry and industrial manufacturing. It is also used in research and development as a starting material for the preparation of new compounds with potential pharmacological and biological activities. Moreover, it is considered as an important chemical in the pharmaceutical industry due to its role as a key precursor in the synthesis of various drug molecules.

InChI:InChI=1/C9H7NO2/c1-7(11)12-9-4-2-3-8(5-9)6-10/h2-5H,1H3

Upstream product

• 69113-59-3 3-iodobenzonitrile 
• 6018-89-9 nickel(II) acetate tetrahydrate 
• 15761-39-4 N-tert-butoxycarbonyl-proline 
• 122-46-3 3-acetoxytoluene 
• 873-62-1 m-cyanophenol 
• 108-24-7 acetic anhydride 
• 830-03-5 4-nitrophenol acetate 
• 22241-18-5 3-hydroxybenzaldehyde oxime 

Downstream Products

• 873-62-1 m-cyanophenol 
• 64-19-7 acetic acid 
• 14221-77-3 4-acetyl-3-hydroxybenzonitrile 
• 2466-76-4 N-Acetylimidazole 
• 1119-49-9 N-butylacetamide 
• 588-46-5 N-(phenylmethyl)acetamide 
• 25079-96-3 N-(4-methylbenzyl)acetamide 
• 35103-34-5 N-(p-methoxybenzyl)acetamide 
• 57058-33-0 N-(4-chlorobenzyl)acetamide 
• 122-79-2 Phenyl acetate 

Relevant articles and documents

Semi-heterogeneous Dual Nickel/Photocatalysis using Carbon Nitrides: Esterification of Carboxylic Acids with Aryl Halides

Cross-coupling reactions mediated by dual nickel/photocatalysis are synthetically attractive but rely mainly on expensive, non-recyclable noble-metal complexes as photocatalysts. Heterogeneous semiconductors, which are commonly used for artificial photosynthesis and wastewater treatment, are a sustainable alternative. Graphitic carbon nitrides, a class of metal-free polymers that can be easily prepared from bulk chemicals, are heterogeneous semiconductors with high potential for photocatalytic organic transformations. Here, we demonstrate that graphitic carbon nitrides in combination with nickel catalysis can induce selective C?O cross-couplings of carboxylic acids with aryl halides, yielding the respective aryl esters in excellent yield and selectivity. The heterogeneous organic photocatalyst exhibits a broad substrate scope, is able to harvest green light, and can be recycled multiple times. In situ FTIR was used to track the reaction progress to study this transformation at different irradiation wavelengths and reaction scales.

SPIROKETONE ACETYL-COA CARBOXYLASE INHIBITORS

The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating mammals suffering from the condition of being overweight.

Kinetics and mechanism of aminolysis of phenyl acetates and phenyl trimethylacetates in dimethyl suldoxide

Kinetic studies have been carried out on the reactions of phenyl acetates and phenyl trimethylacetates in dimethyl sulfoxide.The rate ratios between the two acyl compounds, and the positive sign and large magnitude of the cross-interaction constants, ρXZ, between substituents X in the nucleophile and Z in the leaving group are considered to favour the rate-limiting expulsion of aryl oxide from the tetrahedral intermediate T+/-.The aprotic solvent used makes the proposed mechanism with a cyclic transition state more attractive especially in view of the greater charge dispersion and assistance to leaving group departure provided in such a structure.