22260-42-0

Basic information

• Product Name: curarine
• Synonyms: Curarine; (+)-2,2'-Dimethylbebeerine; (+)-Curarine; 2,2'-Dimethylbebeerinium; Curarine (C33 alkaloid); Curarine (C38 alkaloid); Curarine (C38 alkaloid), (+)-; N,N'-Dimethylbebeerinium; Tubocuraranium, 7',12'-dihydroxy-6,6'-dimethoxy-2,2,2',2'-tetramethyl-, (1'alpha)-; 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,1,14,14-tetramethyl-, (13aS,25aS)-; 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido(3',2':14,15)(1,11)dioxacycloeicosino(2,3,4-ij)isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,1,14,14-tetramethyl-, (13aS-(13aR*,25aR*))-; Bebeerinium, 2,2'-dimethyl- (8CI); Tubocuraranium, 7',12'-dihydroxy-6,6'-dimethoxy-2,2,2',2'-tetramethyl-, (1'-alpha)- (9CI); (1'alpha)-7',12'-dihydroxy-6,6'-dimethoxy-2,2,2',2'-tetramethyltubocuraran-2,2'-diium
• CAS NO: 22260-42-0
• Molecular Formula: C₃₈H₄₄N₂O₆
• Molecular Weight: 624.7647
• EINECS: 244-880-6
• Mol File: 22260-42-0.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: curarine(CAS DataBase Reference)
• NIST Chemistry Reference: curarine(22260-42-0)
• EPA Substance Registry System: curarine(22260-42-0)

Safety Data

• Hazardous Substances Data: 22260-42-0(Hazardous Substances Data)

Usage

General Description

Curarine is a naturally occurring alkaloid found in various plant species, particularly in the South American vine Chondrodendron tomentosum. It is a potent neurotoxin that blocks acetylcholine receptors at the neuromuscular junction, leading to muscle paralysis. Historically, curarine has been used as a poison for hunting and warfare by indigenous tribes in South America. In modern medicine, it has found use as a muscle relaxant during surgical procedures and for the treatment of muscle spasms. Due to its toxicity, curarine must be used with caution and under careful supervision by trained medical personnel.