22318-87-2

Basic information

• Product Name: Benzene, 4-[2-(3,5-dimethoxyphenyl)ethyl]-1,2-dimethoxy-
• CAS NO: 22318-87-2
• Molecular Formula: C18H22O4
• Molecular Weight: 302.37
• Mol File: 22318-87-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzene, 4-[2-(3,5-dimethoxyphenyl)ethyl]-1,2-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 4-[2-(3,5-dimethoxyphenyl)ethyl]-1,2-dimethoxy-(22318-87-2)
• EPA Substance Registry System: Benzene, 4-[2-(3,5-dimethoxyphenyl)ethyl]-1,2-dimethoxy-(22318-87-2)

Safety Data

• Hazardous Substances Data: 22318-87-2(Hazardous Substances Data)

Upstream product

• 20767-18-4 cis-trans-3,3',4',5-tetramethoxystilbene 
• 24131-30-4 (3,5-dimethoxybenzyl)triphenylphosphonium bromide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 4670-10-4 (3,5-dimethoxyphenyl)acetic acid 
• 185249-83-6 3,5-dimethoxybenzyl trimethylsilyl ether 
• 185249-90-5 1-(3,4-dimethoxyphenyl)-2-(3',5'-dimethoxyphenyl)ethan-1-ol 
• 705-76-0 3,5-dimethoxybenzyl alcohol 
• 83088-26-0 (E)-tetramethylpiceatannol 
• 186581-53-3 diazomethane 
• 83088-28-2 gigantol 

Downstream Products

• 22318-80-5 Dihydropiceatannol 
• 22318-88-3 3,4,3',5'-Tetramethoxy-2',6'-diioddibenzyl 

Relevant articles and documents

Prevention of Marine Biofouling Using the Natural Allelopathic Compound Batatasin-III and Synthetic Analogues

The current study reports the first comprehensive evaluation of a class of allelopathic terrestrial natural products as antifoulants in a marine setting. To investigate the antifouling potential of the natural dihydrostilbene scaffold, a library of 22 syn

Simple synthesis of 5-substituted resorcinols: A revisited family of interesting bioactive molecules

The reaction of 3,5-dimethoxybenzyl trimethylsilyl ether (3) with different aldehydes (n-PrCHO, n-C11H23CHO, MeCHO, PhCHO) in the presence of lithium powder and a catalytic amount of naphthalene (4 mol %) gave, after hydrolysis, the expected alcohols 4 in moderate yields. The dehydroxylation of these compounds through the corresponding mesylates 5 or directly from benzylic derivatives by catalytic hydrogenation, afforded compounds 6, which are finally demethylated to yield 5-alkyl-3,5-dihydroxyresorcinols, such as olivetol (7a), grevillol (7b), 1,3-dihydroxy-5-propylbenzene (7c), or dihydropinosilvine (7d). Dehydration of alcohol derivatives 4 followed by demethylation led to hydroxylated stilbene-type structures, such as pinosilvine (9d), resveratrol (9e), or piceatannol (9f), which in some cases can be hydrogenated to give saturated molecules such as combretastanin B-4 tetramethyl ether (6f) or chrysotobibenzyl (6g). Finally, when the naphthalene-catalyzed lithiation of compound 3 was performed in the presence of other electrophiles [Me3SiCl, t-BuCHO, CH3(CH2)4CHO, 4-Me3SiOC6H4CHO, (CH2)5CO, PhN = C = O, PhN = CHPh], the expected reaction products 12 were isolated, after hydrolysis.

Syntheses of Some Biologically Active Compounds from Stilbenes Isolated from the Bark of Picea abies

From the four stilbenes 1-4 isolated from the bark of Picea abies seven compounds 5-11 were obtained by hydrogenation or permethylation. 1H-, 13C-NMR and mass spectra were used for their characterization.The antileukemic activity of each compound was preliminary tested.Some compounds were further tested for their anti-HIV activity.Key Words: Stilbenes/Ethanes, 1,2-diphenyl/Antileukemic activity/HIV