223259-63-0

Basic information

• Product Name: 1,1'-SPIROBIINDANE-7,7'-DIOL
• Synonyms: 1,1'-SPIROBIINDANE-7,7'-DIOL;(1S)-2,2',3,3'-tetrahydro-1,1'-Spirobi[1H-indene]-7,7'-diol;(S)-2,2',3,3'-TETRAHYDRO-1,1'-SPIROBI[INDENE]-7,7'-DIOL, >=95%;S-2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol;S-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol; 1,1'-Spirobi[1H-indene]-7,7'-diol,2,2',3,3'-tetrahydro-;1,1'-Spirobi[1H-indene]-7,7'-diol, 2,2',3,3'-tetrahydro-, (1S)-;(S)-2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 99%e.e.
• CAS NO: 223259-63-0
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.30774
• Product Categories: BINOL Series;Chiral Oxygen;Chiral Spiro Ligand
• Mol File: 223259-63-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 155-156℃
• Boiling Point: 433.0±45.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 9.70±0.20(Predicted)
• CAS DataBase Reference: 1,1'-SPIROBIINDANE-7,7'-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-SPIROBIINDANE-7,7'-DIOL(223259-63-0)
• EPA Substance Registry System: 1,1'-SPIROBIINDANE-7,7'-DIOL(223259-63-0)

Safety Data

• Hazardous Substances Data: 223259-63-0(Hazardous Substances Data)

Usage

Description

1,1'-SPIROBIINDANE-7,7'-DIOL is a unique organic compound characterized by its spirobiindane scaffold, which consists of two indane rings connected by a spiro linkage. This structure endows the molecule with distinct chemical and physical properties, making it a versatile building block in various applications.

Uses

Used in Chemical Synthesis:
1,1'-SPIROBIINDANE-7,7'-DIOL is used as a chiral scaffold for the synthesis of new classes of chiral phosphoric acids. Its unique structure and properties contribute to the development of novel catalysts for asymmetric reactions.
Used in Pharmaceutical Industry:
1,1'-SPIROBIINDANE-7,7'-DIOL is employed as a catalyst in the asymmetric Friedel-Crafts reaction of indoles with imines. This reaction is crucial in the synthesis of 3-indolyl methanamines, which are important building blocks for the development of pharmaceutical compounds with potential therapeutic applications.
Used in Catalyst Development:
The compound is utilized in the development of new catalysts for various chemical reactions, particularly those involving the formation of chiral molecules. Its spirobiindane scaffold provides a stable and versatile platform for the attachment of functional groups, enhancing the efficiency and selectivity of the catalysts.

Upstream product

• 223137-81-3 7,7'-dimethoxy-1,1'-spirobiindane 
• 223137-67-5 1,5-bis(3-methoxyphenyl)-3-pentanone 
• 591-31-1 3-methoxy-benzaldehyde 
• 458533-66-9 (1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one 
• 223137-71-1 1,5-bis-(2-bromo-5-methoxyphenyl)-3-pentanone 
• 223137-76-6 4,4'-dibromo-7,7'-dimethoxy-1,1'-spirobiindane 
• 116836-15-8 1,5-bis(3-methoxyphenyl)-1,4-pentadien-3-one 
• 100-83-4 meta-hydroxybenzaldehyde 
• 1427054-08-7 1,5-bis(3-hydroxyphenyl)pentan-3-one 
• 223137-87-9 (R)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 
• 881915-97-5 (1E,4E)-1,5-bis(3-hydroxyphenyl)penta-1,4-dien-3-one 
• 1427054-10-1 1,5-bis(2-bromo-5-hydroxyphenyl)pentan-3-one 
• 636601-27-9 (S)-4,4'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 

Downstream Products

• 223137-87-9 (R)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 
• 223137-87-9 2,2′,3,3′-tetrahydro-1,1′-spirobi[indene]-7,7′-diol 
• 500997-68-2 N,N-dicyclohexyl-[(R)-1,1'-spirobiindane-7,7'-diyl]phosphoramidite 
• 656233-47-5 (11aR)-(+)-10,11,12,13-tetrahydrodiindeno[7,1-de:1', 7'-fg][1,3,2]dioxaphosphocin-5-bis[(R)-1-phenylethyl]amine 
• 656233-47-5 N,N-di[(R)-1-phenylethyl]-[(S)-1,1'-spirobiindane-7,7'-diyl]phosphoramidite 
• 477559-80-1 N,N-diethyl-[(R)-1,1'-spirobiindane-7,7'-diyl]phosphoramidite 
• 656233-53-3 phenyl-[(R)-1,1'-spirobiindane-7,7'-diyl]phosphite 
• 920985-42-8 (R)-1,1'-spirobiindane-7,7'-dicaboxylic acid 
• 940880-69-3 (R_a,S,S)-7,7'-bis(4-phenyl-4,5-dihydro-1,3-oxazolin-2-yl)-1,1'-spirobiindane 
• 1286189-15-8 6,6'-dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol 
• 1286189-16-9 C₃₃H₂₀F₁₂O₂ 

Relevant articles and documents

A ligand synthesis of butadiene adhesive

The invention relates to a synthesis method of ligand butadiene adhesive, to 3 - hydroxybenzaldehyde with acetone as the starting material, condensation to obtain the 1, 5 - double-(3 - hydroxy-phenyl) - 1, 4 - isoprene ketone, the 1, 5 - double-(3 - hydr

Chiral ligand 1,1'-spirobiindane-7,7'-diol synthesis method

The present invention discloses a chiral ligand 1,1'-spirobiindane-7,7'-diol synthesis method, wherein 3-methoxybenzaldehyde is adopted as a starting raw material, and hydroxyaldehyde condensation, hydrogenation reducing, bromination, dehydration cyclizat

CHIRAL COMPOUNDS AND COMPOSITIONS CONTAINING THE SAME

The invention relates to a novel class of compounds useful as chiral dopants, which compounds are available in both enantiomeric forms. Another aspect of the invention relates to such compounds having a enantiomeric excess of one enantiomeric form, which are useful in liquid crystal formulations. Such formulations are advantageous in displays and various other products.