22364-25-6

Basic information

• Product Name: 4-BROMO-2,3-DIMETHYLANILINE
• Synonyms: 4-BROMO-2,3-DIMETHYLANILINE;4-Bromo-2,3-dimethylaniline 98%;(4-bromo-2,3-dimethylphenyl)amine;4-BroMo-2,3-xylidine;4-Brom-2,3-dimethyl-anilin
• CAS NO: 22364-25-6
• Molecular Formula: C₈H₁₀BrN
• Molecular Weight: 200.0757
• Product Categories: blocks;Bromides
• Mol File: 22364-25-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 215-217
• Boiling Point: 265.519 °C at 760 mmHg
• Flash Point: 114.382 °C
• Appearance: /
• Density: 1.424 g/cm³
• Vapor Pressure: 0.009mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: Keep Cold
• PKA: 3.87±0.10(Predicted)
• CAS DataBase Reference: 4-BROMO-2,3-DIMETHYLANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2,3-DIMETHYLANILINE(22364-25-6)
• EPA Substance Registry System: 4-BROMO-2,3-DIMETHYLANILINE(22364-25-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 22364-25-6(Hazardous Substances Data)

Usage

General Description

4-Bromo-2,3-dimethylaniline, also known as 2,3-dimethyl-4-bromoaniline, is a chemical compound with the molecular formula C8H10BrN. It is a derivative of aniline, with bromine and methyl groups attached at the 4 and 2,3 positions, respectively. 4-BROMO-2,3-DIMETHYLANILINE is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and dyes. It is also used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Due to its chemical structure, 4-bromo-2,3-dimethylaniline is primarily considered a hazardous substance and should be handled and stored with caution to prevent adverse health effects and environmental contamination.

InChI:InChI=1/C8H10BrN/c1-5-6(2)8(10)4-3-7(5)9/h3-4H,10H2,1-2H3

Upstream product

• 87-59-2 2,3-Dimethylaniline 
• 134-98-5 N-(2,3-dimethylphenyl)acetamide 
• 22369-96-6 4-bromo-2,3-dimethylacetanilide 

Downstream Products

• 366-29-0 N,N,N',N'-tetramethylbenzidine 
• 576-23-8 2,3-dimethylbromobenzene 
• 75024-22-5 1,4-dibromo-2,3-dimethylbenzene 
• 250593-00-1 2,3-dimethyl-4-methylsulfanylbromobenzene 
• 1160573-43-2 1-bromo-4-iodo-2,3-dimethylbenzene 
• 75-65-0 tert-butyl alcohol 
• 52964-29-1 1,4-dibromo-2,3-bis(dibromomethyl)benzene 
• 1082041-34-6 5-bromo-4-methyl-1H-indazole 
• 1385026-26-5 4-bromo-N-tert-butyloxycarbonyl-2,3-bis(bromomethyl)aniline 
• 1385026-24-3 4-bromo-N-tert-butoxycarbonyl-2,3-dimethylaniline 
• 916482-42-3 C₁₆H₁₇BrClN₃O₂S 
• 100958-93-8 1,4-dibromo-2,3-dimethyl-5,6-dinitro-benzene 
• 109844-88-4 2,3-dimethyl-terephthalic acid monomethyl ester 
• 99068-44-7 2,3-dimethyl-terephthalic acid diamide 

Relevant articles and documents

Amplifying fluorescent conjugated polymer sensor for singlet oxygen detection

A "higher energy gap" concept was applied towards designing an efficient turn-on amplifying sensor for singlet oxygen-an important biomedical and environmental monitoring analytical target. The concept is based on modulation of intramolecular energy trans

Merging N-Hydroxyphthalimide into Metal-Organic Frameworks for Highly Efficient and Environmentally Benign Aerobic Oxidation

Two highly efficient metal-organic framework catalysts TJU-68-NHPI and TJU-68-NDHPI have been successfully synthesized through solvothermal reactions of which the frameworks are merged with N-hydroxyphthalimide (NHPI) units, resulting in the decoration of pore surfaces with highly active nitroxyl catalytic sites. When t-butyl nitrite (TBN) is used as co-catalyst, the as-synthesized MOFs are demonstrated to be highly efficient and recyclable catalysts for a novel three-phase heterogeneous oxidation of activated C?H bond of primary and secondary alcohols, and benzyl compounds under mild conditions. Based on the high efficiency and selectivity, an environmentally benign system with good sustainability, mild conditions, simple work-up procedure has been established for practical oxidation of a wide range of substrates.

A facile, regioselective and controllable bromination of aromatic amines using a CuBr2/Oxone system

A combination of cupric bromide and Oxone serves as a facile, mild and effective reagent for the bromination of aromatic amines. Primary, secondary and tertiary aromatic amines are all suitable substrates. The reaction possesses high regioselectivity and functional group tolerance, and mono- and multi-brominated products can be obtained controllably in moderate to excellent yields. The Royal Society of Chemistry 2013.