223671-18-9 Usage
Description
7-Bromoisoquinoline N-oxide, also known as 7-broMoisoquinolin-2-iuM-2-olate, is an organic compound derived from the isoquinoline family. It is characterized by the presence of a bromine atom at the 7th position and an N-oxide functional group. 7-broMoisoquinolin-2-iuM-2-olate is known for its unique chemical properties and reactivity, making it a valuable intermediate in the synthesis of various pharmaceuticals and organic compounds.
Uses
Used in Pharmaceutical Synthesis:
7-Bromoisoquinoline N-oxide is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity allow for the development of new drugs with potential applications in treating various diseases and medical conditions.
Used in Organic Chemistry:
In the field of organic chemistry, 7-broMoisoquinolin-2-iuM-2-olate is used as a reactant in the direct regioselective phosphonation of heteroaryl N-oxides with H-phosphonates. This reaction is significant as it enables the selective functionalization of these compounds, which can be further utilized in the synthesis of complex organic molecules and materials.
Used in Chemical Research:
7-Bromoisoquinoline N-oxide is also employed in chemical research as a model compound to study various reaction mechanisms and explore new synthetic routes. Its unique properties make it an ideal candidate for investigating the reactivity of heteroaryl N-oxides and their potential applications in various chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 223671-18-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,6,7 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 223671-18:
(8*2)+(7*2)+(6*3)+(5*6)+(4*7)+(3*1)+(2*1)+(1*8)=119
119 % 10 = 9
So 223671-18-9 is a valid CAS Registry Number.
223671-18-9Relevant articles and documents
Light-induced [2 + 2] cycloadditions for the construction of cyclobutane-fused pyridinyl sulfonyl fluorides
Liu, Jing,Wang, Shi-Meng,Qin, Hua-Li
supporting information, p. 4019 - 4023 (2020/06/09)
Cyclobutanes are an important class of motifs present in a wide range of natural products and other biologically significant molecules. A photocatalytic [2 + 2] cycloaddition between pyridones or isoquinolones and ethenesulfonyl fluoride was achieved, providing a portal to a class of unique cyclobutane-fused pyridinyl sulfonyl fluorides with quaternary rigid rings (30 examples). Further applications of these novel sulfonyl fluoride molecules in SuFEx click chemistry were also accomplished, providing the corresponding sulfonates and sulphonamides with reasonable yields.
