223734-99-4

Basic information

• Product Name: ethylmethyl-2,6-bis-[(2-phthalimidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• Synonyms: ethylmethyl-2,6-bis-[(2-phthalimidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• CAS NO: 223734-99-4
• Molecular Weight: 728.155
• Mol File: 223734-99-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethylmethyl-2,6-bis-[(2-phthalimidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethylmethyl-2,6-bis-[(2-phthalimidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate(223734-99-4)
• EPA Substance Registry System: ethylmethyl-2,6-bis-[(2-phthalimidoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate(223734-99-4)

Safety Data

• Hazardous Substances Data: 223734-99-4(Hazardous Substances Data)

Upstream product

• 721958-73-2 methyl-3-amino-4-[2-(phthalimido)ethoxy]acetoacetate 
• 400024-08-0 ethyl 2-(2-chlorobenzylidene)-4-[(2-phthalimido)ethoxy]acetoacetate 

Downstream Products

• 721958-74-3 ethylmethyl-2,6-bis-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylate 

Relevant articles and documents

ISOLATION OF DIHYDROPYRIDINE DERIVATIVE AND PREPARATION SALTS THEREOF

The title compound is isolated in pure form by using a crystallization process and converted to its pharmaceutically acceptable salts. The crystallization process affects stability and purity of the amlodipine salts. All known impurities and one unknown impurity, which forms during the synthesis of the amlodipine salts, were isolated, characterized, and synthesized. A new method allowing the quantitative HPLC analysis of all related impurities of amlodipine salts in a single chromatogram was developed.