2243-81-4

Basic information

• Product Name: NAPHTHALENE-1-CARBOXAMIDE
• Synonyms: 1-NAPTHAMIDE;1-NAPHTHALIMIDE;1-NAPHTHAMIDE;A-NAPHTHAMIDE;ALPHA-NAPHTHAMIDE;ALPHA-NAPTHOIC ACID AMIDE;NAPHTHALENE-1-CARBOXAMIDE;1-Naphthalenecarboxamide
• CAS NO: 2243-81-4
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.2
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 2243-81-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 201-204°C
• Boiling Point: 301.18°C (rough estimate)
• Flash Point: 196.6°C
• Appearance: /
• Density: 1.1242 (rough estimate)
• Vapor Pressure: 1.18E-06mmHg at 25°C
• Refractive Index: 1.4900 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• PKA: 16.00±0.30(Predicted)
• BRN: 2044731
• CAS DataBase Reference: NAPHTHALENE-1-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: NAPHTHALENE-1-CARBOXAMIDE(2243-81-4)
• EPA Substance Registry System: NAPHTHALENE-1-CARBOXAMIDE(2243-81-4)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 22-24/25
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 2243-81-4(Hazardous Substances Data)

Usage

Uses

1-Naphthamide can be used to induce plant rooting.

InChI:InChI=1/C11H9NO/c12-11(13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H,(H2,12,13)

Upstream product

• 91-20-3 naphthalene 
• 51-79-6 urethane 
• 74-88-4 methyl iodide 
• 86-53-3 1-Cyanonaphthalene 
• 201230-82-2 carbon monoxide 
• 90-11-9 1-Bromonaphthalene 
• 118-31-0 (naphth-1-yl)methylamine 
• 66-77-3 1-naphthaldehyde 
• 27466-85-9 N-benzyl-1-naphthamide 
• 4780-79-4 1-naphthalene methanol 
• 127099-85-8 N-Cyanoguanidine 
• 13504-46-6 1-naphtylaldehyde oxime 

Downstream Products

• 86-55-5 1-naphthalenecarboxylic acid 
• 4780-79-4 1-naphthalene methanol 
• 86-53-3 1-Cyanonaphthalene 
• 105983-33-3 α-naphtamido-1 (cyclohexene-1 yl)-2 cyclohexene 
• 1975-44-6 5-nitro-1-naphthoic acid 
• 46389-16-6 ethyl-1-naphthalenecarboximidate 
• 13026-12-5 3-(1-naphthyl)propenoic acid 
• 66-77-3 1-naphthaldehyde 
• 1253388-75-8 C₃₉H₂₅NO 
• 20300-10-1 1-naphthalenecarbothioamide 
• 40054-08-8 2-(naphthalen-1-yl)-4,5-dihydrooxazole 
• 3007-97-4 ethyl 1-naphthoate 
• 642-29-5 1-benzoylnaphthalene 
• 3400-33-7 N-methyl-1-naphthalenecarboxamide 

Relevant articles and documents

Et4NI-catalyzed amidation of aldehydes and alcohols with ammonium salts

An efficient method for the oxidative amidation of benzylic aldehydes or alcohols with ammonium salts has been developed for the synthesis of primary amides using Et4NI as the catalyst and tert-butyl hydroperoxide as the oxidant. This amidation reaction is operationally straightforward and provides primary amides in moderate to good yields under mild conditions.

Benzamide synthesis by direct electrophilic aromatic substitution with cyanoguanidine

Cyanoguanidine is an inexpensive commodity chemical and it is found to be a useful reagent for the direct Friedel-Crafts carboxamidation of arenes. The reaction works best in an excess of Bronsted superacid, an observation suggesting the involvement of a superelectrophilic intermediate. Theoretical calculations indicate that the most stable diprotonated species involves protonation at the guanidine and cyano nitrogen atoms.

Room-temperature debenzylation of N-benzylcarboxamides by N-bromosuccinimide

A simple and highly efficient method has been developed with which to cleave the N-benzyl group on N-mono- or disubstituted carboxamides using N-bromosuccinimide (NBS) at room temperature. All the 31 substrates examined showed moderate to excellent deprotection yields. Our study also indicated that the debenzylation may involve an oxygen/light initiated free radical mechanism. Georg Thieme Verlag Stuttgart.