2245-30-9

Basic information

• Product Name: 3,3-DIMETHYL-1,2-EPOXYBUTANE
• Synonyms: 1,1-Dimethylethyl-oxirane;2-tert-Butyloxirane;3,3-Dimethylbutene oxide;Butane, 1,2-epoxy-3,3-dimethyl-;Oxirane, (1,1-dimethylethyl)-;Oxirane, 2-(1,1-dimethylethyl)-;tert-Butylethylene oxide;tert-Butyloxirane
• CAS NO: 2245-30-9
• Molecular Formula: C₆H₁₂O
• Molecular Weight: 100.16
• EINECS: 218-831-4
• Mol File: 2245-30-9.mol
• Article Data: 39

Chemical Properties

• Boiling Point: 95-96°C
• Flash Point: -1°C
• Appearance: /
• Density: 0,822 g/cm3
• Vapor Pressure: 62mmHg at 25°C
• Refractive Index: 1.4010
• BRN: 102478
• CAS DataBase Reference: 3,3-DIMETHYL-1,2-EPOXYBUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DIMETHYL-1,2-EPOXYBUTANE(2245-30-9)
• EPA Substance Registry System: 3,3-DIMETHYL-1,2-EPOXYBUTANE(2245-30-9)

Safety Data

• Hazard Codes: Xn
• Statements: 11-36/37/38-22
• Safety Statements: 16-23-33-36
• RIDADR: 1993
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 2245-30-9(Hazardous Substances Data)

Usage

Uses

3,3-Dimethyl-1,2-epoxybutane is used as pharm and intermediates.

InChI:InChI=1/C6H12O/c1-6(2,3)5-4-7-5/h5H,4H2,1-3H3/t5-/m0/s1

Upstream product

• 558-37-2 tert-butylethylene 
• 75-09-2 dichloromethane 
• 535-80-8 3-chlorobenzoate 
• 36402-31-0 3,3-dimethyl-1-chloro-2-butanol 
• 2245-30-9 1,2-epoxy-3,3-dimethylbutane 
• 32659-48-6 (S)-2-chloro-3,3-dimethylbutanoic acid 
• 20859-02-3 L-tert-Leucine 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 139040-45-2 (R)-1,1,1-trichloromethyl-3,3-dimethyl-2-butanol 
• 36965-30-7 3,3-dimethyl-1,1,1-trichloro-2-butanone 
• 152611-54-6 Chloro-acetic acid (R)-1-chloromethyl-2,2-dimethyl-propyl ester 
• 152488-35-2 Chloro-acetic acid 1-chloromethyl-2,2-dimethyl-propyl ester 
• 31612-63-2 (R)-3,3-dimethylbutane-1,2-diol 
• 40348-71-8 (R)-(-)-(tosyloxy)-3,3-dimethyl-butan-2-ol 

Downstream Products

• 144788-75-0 (1S,3S)-1-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-4,4-dimethyl-1-phenyl-pentan-3-ol 
• 144712-78-7 (1S,3R)-1-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-4,4-dimethyl-1-phenyl-pentan-3-ol 
• 130748-11-7 1-[(2-Hydroxy-3,3-dimethyl-butyl)-phenyl-phosphanyl]-3,3-dimethyl-butan-2-ol 
• 123271-33-0 diphenyl (2-hydroxy-3,3-dimethylbutyl)phosphine 
• 2245-30-9 (R)-tert-butyloxirane 
• 40102-55-4 (S)-(-)-3,3-dimethyl-1,2-epoxybutane 
• 31612-63-2 (R)-3,3-dimethylbutane-1,2-diol 
• 31612-63-2 (2S)-3,3-dimethylbutane-1,2-diol 
• 2987-16-8 3,3-dimethylbutyrylaldehyde 
• 62694-35-3 4-tert-butyl-β-propiolactone 
• 123271-34-1 3,3-Dimethyl-1-diphenylphosphinoylbutan-2-ol 
• 79989-30-3 1-(4-chlorophenoxy)-3,3-dimethyl-butan-2-ol 
• 1038436-25-7 (R)-(-)-1-[2-(benzyloxy)-5-methoxyphenoxy]-3,3-dimethylbutan-2-ol 
• 1038436-37-1 (R)-(-)-1-[2-(benzyloxy)-5-bromophenoxy]-3,3-dimethylbutan-2-ol 

Relevant articles and documents

A Facile Enzyme Assisted Route to (R)- and (S)-t-Butyloxirane and related β-Amino Alcohols - Catalysts for the Enantioselective Addition of Dialkylzinc Reagents to Aldehydes

(R) and (S)-t-butyloxirane have been prepared in high enantiomeric purity from racemic t-butyloxirane (+/-)-3 by an enzymatic route. (S)-3 has been used for the preparation of the chiral β-amino alcohols (R)- and (S)-1,2, which are catalysts for the enantioselective addition of dialkylzinc reagents to aldehydes.

Remote Amino Acid Recognition Enables Effective Hydrogen Peroxide Activation at a Manganese Oxidation Catalyst

Precise delivery of a proton plays a key role in O2 activation at iron oxygenases, enabling the crucial O?O cleavage step that generates the oxidizing high-valent metal–oxo species. Such a proton is delivered by acidic residues that may either

Aromatic Donor-Acceptor Interaction-Based Co(III)-salen Self-Assemblies and Their Applications in Asymmetric Ring Opening of Epoxides

Aromatic donor-acceptor interaction as the driving force to assemble cooperative catalysts is described. Pyrene/naphthalenediimide functionalized Co(III)-salen complexes self-assembled into bimetallic catalysts through aromatic donor-acceptor interactions and showed high catalytic activity and selectivity in the asymmetric ring opening of various epoxides. Control experiments, nuclear magnetic resonance (NMR) spectroscopy titrations, mass spectrometry measurement, and X-ray crystal structure analysis confirmed that the catalysts assembled based on the aromatic donor-acceptor interaction, which can be a valuable noncovalent interaction in supramolecular catalyst development.

Epoxidation of alkenes catalyzed by some molybdenum(0) and molybdenum(IV) complexes

Catalytic epoxidations of styrene, cyclohexene, 1-octene, and 3,3-dimethyl-1-butene have been explored utilizing a variety of molybdenum(0) and molybdenum(IV) complexes as precatalysts and tert-butylhydroperoxide (TBHP) as oxidant. The catalytic activities of the complexes MoCl4(CH3CN)2, Mo(CO)3(PTA)3 (PTA = 1,3,5-triaza-7-phosphaadamantane), Mo(CO)3(Mes), and a molybdenum(IV) calix[4]arene salt, [Et3NH][Mo{tBuC4}Cl(CH3CN)] have been investigated. The progress of reactions was monitored with reference to an internal standard by means of 1H NMR spectroscopy. Most of the complexes were found to be effective precatalysts with low catalyst loadings, giving rise to good to excellent conversion of alkenes and yield of the epoxides with the formation of minimal amount of corresponding diol and other side products. The catalytic reactions were found to be most efficient between 100 and 110 °C in minimal solvent or without added solvent.