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22592-73-0

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22592-73-0 Usage

Description

(S)-2-Bromopropionyl chloride, with the molecular formula C3H4BrClO, is a colorless liquid characterized by a pungent odor. It is a chemical compound that serves as a crucial reagent in organic synthesis, playing a significant role in the production of various pharmaceuticals, agrochemicals, and fine chemicals. Additionally, it is utilized in the manufacturing of polymers and aids in the synthesis of organic compounds.

Uses

Used in Pharmaceutical Industry:
(S)-2-Bromopropionyl chloride is used as a building block for the synthesis of various pharmaceuticals. Its reactivity and versatility allow for the creation of a wide range of medicinal compounds, contributing to the development of new drugs and treatments.
Used in Agrochemical Industry:
In the agrochemical sector, (S)-2-Bromopropionyl chloride is employed as a key component in the production of different agrochemicals. Its incorporation into these products helps enhance their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Fine Chemicals Production:
(S)-2-Bromopropionyl chloride is used as a versatile building block in the synthesis of various fine chemicals. Its unique properties enable the creation of a diverse array of specialty chemicals, which find applications in industries such as fragrances, dyes, and coatings.
Used in Polymer Manufacturing:
(S)-2-Bromopropionyl chloride is also utilized in the manufacturing process of polymers. Its reactive nature allows for the formation of polymers with specific properties, which can be tailored for use in various applications, including plastics, adhesives, and coatings.
Used in Organic Synthesis:
As a reagent in organic synthesis, (S)-2-Bromopropionyl chloride is employed for the synthesis of organic compounds. Its high reactivity makes it a valuable tool in the creation of new molecules and the modification of existing ones, further expanding the range of chemicals available for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 22592-73-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,5,9 and 2 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22592-73:
(7*2)+(6*2)+(5*5)+(4*9)+(3*2)+(2*7)+(1*3)=110
110 % 10 = 0
So 22592-73-0 is a valid CAS Registry Number.

22592-73-0Relevant articles and documents

Stereoselective synthesis of α-substituted ulosonic acids by magnesio-Reformatsky reactions

Csuk, Rene,Schroeder, Christina,Krieger, Claus

, p. 12947 - 12960 (1997)

A new method of homologation of aldonolactones allowing the incorporation of propionate units with excellent chemo- and stereoselectivity is performed by the magnesium-graphite mediated reaction between Oppolzer sultam derived α-halogenated amides and an aldonolactone.

Method for manufacturing isavuconazole or ravuconazole

-

Paragraph 0072; 0073, (2017/08/27)

The invention provides a method for manufacturing a triazole compound isavuconazole or ravuconazole which is enriched by a diastereoisomer and enantiomer. The method comprises the following steps: a Reformatsky reaction is carried out between ketone and dihalogeno metal propionitrile; an enantiomer mixture is generated, and separation is carried out. The method can obviously reduce steps for synthesis of isavuconazole or ravuconazole, yield of products is improved, and production cost is reduced.

Synthesis of enantiomerically enriched-bromonitriles from amino acids

Tka, Najeh,Kraem, Jamil,Hassine, Bechir Ben

, p. 735 - 743 (2013/01/15)

Two methods were investigated for the preparation of six chiral-bromonitriles with different optic purities. The nitrous deamination of amino acids gives-bromoacids, which react with chlorosulfonyl isocyanate followed by triethylamine to afford-bromonitriles with moderate enantiomeric excess. However, the dehydration of corresponding-bromoamids using thionyl chloride gives-bromonitriles with good enantiomeric excess up to 94%. The use of phosphoryl chloride instead of thionyl chloride results in more than 30% racemization as determined by high-performance liquid chromatograpic analysis.

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