22620-32-2

Basic information

• Product Name: 3-Pyridinemethanol,5-fluoro-(8CI,9CI)
• Synonyms: 3-Pyridinemethanol,5-fluoro-(8CI,9CI);5-fluoronicotinyl alcohol;(5-Fluoro-pyridin-3-yl)-methanol;(5-Fluoropyridin-3-yl)met...;5-fluoro-3-PyridineMethanol;(5-Fluoro-3-pyridyl)methanol;(5-Fluoropyridin-3-yl)
• CAS NO: 22620-32-2
• Molecular Formula: C₆H₆FNO
• Molecular Weight: 127.12
• Product Categories: PYRIDINE
• Mol File: 22620-32-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 214.9 °C at 760 mmHg
• Flash Point: 83.8 °C
• Appearance: /
• Density: 1.262 g/cm³
• Vapor Pressure: 0.0894mmHg at 25°C
• Refractive Index: 1.523
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.29±0.10(Predicted)
• CAS DataBase Reference: 3-Pyridinemethanol,5-fluoro-(8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinemethanol,5-fluoro-(8CI,9CI)(22620-32-2)
• EPA Substance Registry System: 3-Pyridinemethanol,5-fluoro-(8CI,9CI)(22620-32-2)

Safety Data

• Statements: 20/21/22-33-37/38
• Safety Statements: 7/8-26-36/37/39-45
• RIDADR: UN2811
• Hazardous Substances Data: 22620-32-2(Hazardous Substances Data)

Usage

Chemical Properties

Yellow liquid

Uses

(5-Fluoropyridin-3-yl)methanol

InChI:InChI=1/C6H6FNO/c7-6-1-5(4-9)2-8-3-6/h1-3,9H,4H2

Upstream product

• 820224-51-9 (2,6-dichloro-5-fluoro-pyridin-3-yl)-methanol 
• 39891-04-8 5-fluoropyridine-3-carboxaldehyde 
• 884494-95-5 5-methyl-nicotinic acid chloride 
• 70-57-5 5-methylpyridinylcarboxamide 
• 402-66-4 5-fluoropyridine-3-carboxylic acid 
• 3222-49-9 5-methylnicotinic acid 
• 3430-19-1 5-methylpyridin-3-amine 
• 407-21-6 5-methyl-3-fluoropyridine 
• 591-22-0 3,5-Lutidine 
• 455-70-9 5-fluoro-3-pyridinecarboxylic acid methyl ester 

Downstream Products

• 1256561-65-5 3-(bromomethyl)-5-fluoro-pyridine hydrobromide 
• 39891-37-7 3-(chloromethyl)-5-fluoropyridine 
• 114995-63-0 (2-Amino-3,5-difluoro-phenyl)-(5-fluoro-pyridin-3-yl)-methanone 
• 39891-04-8 5-fluoropyridine-3-carboxaldehyde 
• 820224-52-0 3-(t-butyldiphenylsilyloxymethyl)-5-fluoropyridine 

Relevant articles and documents

Structural contributions to autocatalysis and asymmetric amplification in the soai reaction

Diisopropylzinc alkylation of pyrimidine aldehydes-the Soai reaction, with its astonishing attribute of amplifying asymmetric autocatalysis-occupies a unique position in organic chemistry and stands as an eminent challenge for mechanistic elucidation. A n

SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS

Substituted 1 H-imidazo[4,5-b]pyridin-2(3H)-ones as NR2B receptor ligands. Such compounds may be used in NR2B receptor modulation and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by NR2B receptor activity.

METHYL SULFANYL PYRMIDMES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS

The present invention relates to pyrimidine derivatives of Formula (Ia) and (Ib) (including tautomers, isomers, prodrugs, and pharmaceutically acceptable salts thereof). Said compounds are useful in the treatment of pain (such as neuropathic pain), inflammation, and epilepsy (by acting as anticonvulsants). Methods of medical treatment making use of said compounds, as well as additional compounds of Formula (IIa) and (IIb), are also disclosed.