2270-40-8 Usage
Description
Diacetoxyscirpenol is a trichothecene mycotoxin, which is a type of toxic chemical compound produced by various Fusarium strains. It is typically found in cereals, where it can be conjugated with glucose and other sugars. Diacetoxyscirpenol is characterized by its white powder appearance.
Uses
1. Used in Agricultural and Food Industry:
Diacetoxyscirpenol is used as a biomarker for [detecting the presence of Fusarium strains and their associated mycotoxins in cereals] because of its production by these strains and its occurrence in contaminated cereals.
2. Used in Research and Development:
Diacetoxyscirpenol is used as a research compound for [studying the effects of mycotoxins on human and animal health] due to its toxic properties and its role as a trichothecene mycotoxin.
3. Used in Analytical Chemistry:
Diacetoxyscirpenol is used as a reference material for [developing and validating analytical methods for the detection and quantification of mycotoxins in food and feed products], given its chemical properties and its presence in contaminated cereals.
4. Used in Mycotoxin Management:
Diacetoxyscirpenol is used as a target for [developing strategies to reduce mycotoxin contamination in the agricultural and food industry], as its presence indicates the potential risk of mycotoxin-related health issues.
5. Used in Pharmaceutical Industry:
Although Diacetoxyscirpenol is a toxic compound, it may be used as a starting material for [the development of new drugs with potential therapeutic applications] by studying its chemical structure and properties, and modifying them to create safer and more effective compounds.
Safety Profile
A deadly poison by ingestion,inhalation, intravenous, intraperitoneal, and subcutaneousroutes. Human systemic effects by intraperitoneal route:muscle weakness, nausea or vomiting, and fever. Anexperimental teratogen. Other experimental reproductiveef
Check Digit Verification of cas no
The CAS Registry Mumber 2270-40-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,7 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2270-40:
(6*2)+(5*2)+(4*7)+(3*0)+(2*4)+(1*0)=58
58 % 10 = 8
So 2270-40-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O7/c1-10-5-6-18(8-23-11(2)20)13(7-10)26-16-14(22)15(25-12(3)21)17(18,4)19(16)9-24-19/h7,13-16,22H,5-6,8-9H2,1-4H3/t13-,14-,15-,16-,17-,18-,19+/m1/s1
2270-40-8Relevant articles and documents
THE FACILE CONVERSION OF T-2 TOXIN AND NEOSOLANIOL INTO ANGUIDINE
Anderson, Derek W.,Black, Robin M.,Leigh, David A.,Stoddart, Fraser J.,Williams, Nancy E.
, p. 2661 - 2664 (1987)
T-2 Toxin (5) and neosolaniol (6) are readily converted into anguidine (1) by a procedure where deoxygenation at the C-8 position is achieved, after conversion of the 3-TBDMS ether 7 of neosolaniol (6) to the β-bromide 11 for reduction to the anguidine precursor 12.
Trichothecene degradation studies. 3. Synthesis of 12,13-deoxy-12,13-methanoanguidine and 12-epianguidine, two optically active analogues of the epoxytrichothecene mycotoxin anguidine
Roush, William R.,Russo-Rodriguez, Sandra
, p. 603 - 606 (2007/10/02)
The title compounds were synthesized in order to further explore the apparent requirement of the trichothecene 12,13-epoxide unit for biological activity. Cyclopropane analogue 4 was prepared via a sequence involving a Simmons-Smith cyclopropanation of the anguidine degradation intermediate 6, whereas the key step in the synthesis of 12-epianguidine (5) was the dimethylsulfonium methylide mediated cyclopropanation of norketone 9. These compounds are among the first skeletally modified, semisynthetic trichothecene analogues to be prepared for biological evaluation.
Total synthesis of the trichothecene mycotoxin anguidine
Brooks,Grothaus,Mazdiyasni
, p. 4472 - 4473 (2007/10/02)
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