227751-65-7

Basic information

• Product Name: 3-(3-Hydroxy-4-nitro-phenyl)-acrylic acid ethyl ester
• Synonyms: 3-(3-Hydroxy-4-nitro-phenyl)-acrylic acid ethyl ester
• CAS NO: 227751-65-7
• Molecular Weight: 237.212
• Mol File: 227751-65-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(3-Hydroxy-4-nitro-phenyl)-acrylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-Hydroxy-4-nitro-phenyl)-acrylic acid ethyl ester(227751-65-7)
• EPA Substance Registry System: 3-(3-Hydroxy-4-nitro-phenyl)-acrylic acid ethyl ester(227751-65-7)

Safety Data

• Hazardous Substances Data: 227751-65-7(Hazardous Substances Data)

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 704-13-2 5-formyl-2-nitrophenol 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 108807-27-8 ethyl 3-(4-amino-3-hydroxyphenyl)propanoate 
• 383667-13-8 ethyl (E)-3-(3-methoxy-4-nitrophenyl)acrylate 

Relevant articles and documents

Novel Compounds as Autotaxin Inhibitors and Pharmaceutical Compositions Comprising the Same

The present invention relates to a novel autotaxin inhibitor compound for preventing and treating disease or symptoms due to an increase in concentration of lysophosphatidic acid or activation of autotaxin. The present invention further relates to a pharmaceutical composition containing the same. The novel compound of the present invention is an autotaxin inhibitor which inhibits production of lysophosphatidic acid, and thus is useful for treating or preventing cardiovascular disease, cancer, metabolic disease, kidney disease, liver disease, inflammatory diseases, nervous disease, respiratory disease, desmoid disease, eye disease, cholestatic symptoms, other types of chronic pruritus or acute, or chronic rejection of transplanted organs.COPYRIGHT KIPO 2017