22871-77-8

Basic information

• Product Name: 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER
• Synonyms: 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER;1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL ESTER;5,5-Dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane
• CAS NO: 22871-77-8
• Molecular Formula: C₁₅H₁₇BO₂
• Molecular Weight: 240.11
• EINECS: -0
• Mol File: 22871-77-8.mol
• Article Data: 24

Chemical Properties

• Melting Point: 67-69°C
• Boiling Point: 387.6°C at 760 mmHg
• Flash Point: 188.2°C
• Appearance: /
• Density: 1.08g/cm³
• Vapor Pressure: 7.26E-06mmHg at 25°C
• Refractive Index: 1.565
• Storage Temp.: 2-8°C
• BRN: 3053756
• CAS DataBase Reference: 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER(22871-77-8)
• EPA Substance Registry System: 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER(22871-77-8)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 22871-77-8(Hazardous Substances Data)

Usage

General Description

1-Naphthaleneboronic Acid Neopentyl Glycol Cyclic Ester is a chemical compound commonly used in organic synthesis. Its structural formula is C14H17BO4 and it has a molecular weight of 254.10 g/mol. The compound features a boronic acid ester and a napthylene ring in its structure, which allows it to participate in a variety of chemical reactions. Like other boronic acids and their derivatives, it finds widespread applications in pharmaceutical research, including in the preparation of cancer and anti fungal drugs. Handling this compound requires a considerable degree of caution due to its reactive nature.

InChI:InChI=1/C15H17BO2/c1-15(2)10-17-16(18-11-15)14-9-5-7-12-6-3-4-8-13(12)14/h3-9H,10-11H2,1-2H3

Upstream product

• 5419-55-6 Triisopropyl borate 
• 90-11-9 1-Bromonaphthalene 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 2216-69-5 1-Methoxynaphthalene 
• 201733-56-4 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane 
• 98223-72-4 N-(1-naphthyl)morpholine 
• 92163-14-9 N-naphthylpyrrole 
• 36773-67-8 1-naphthoic acid,phenyl ester 
• 509073-87-4 2-(naphthalen-1-yloxy)pyridine 
• 572-52-1 1-(4-fluorophenyl)naphthalene 
• 321-38-0 1-Fluoronaphthalene 
• 90-15-3 α-naphthol 
• 74734-13-7 naphthalen-8-yl pivalate 
• 4250-53-7 (1-naphthyl)dichloroborane 

Downstream Products

• 605-02-7 1-phenylnaphthalene 

Relevant articles and documents

Cobalt-Catalyzed C(sp2)-C(sp3) Suzuki-Miyaura Cross Coupling

A cobalt-catalyzed method for the C(sp2)-C(sp3) Suzuki-Miyaura cross coupling of aryl boronic esters and alkyl bromides is described. Cobalt-ligand combinations were assayed with high-throughput experimentation, and cobalt(II) sources with trans-N,N′-dimethylcyclohexane-1,2-diamine (DMCyDA, L1) produced optimal yield and selectivity. The scope of this transformation encompassed steric and electronic diversity on the aryl boronate nucleophile as well as various levels of branching and synthetically valuable functionality on the electrophile. Radical trap experiments support the formation of electrophile-derived radicals during catalysis.

Palladium-catalysed reactions of conjugated enyne oxiranes with organoborons: A diastereoselective method of the synthesis of 2,4,5-trienol derivatives

A palladium-catalysed reaction of conjugated enyne oxiranes with organoboron reagents is described. This method allows aryl-substituted vinylallenes containing a hydroxyl group on the allylic position to be synthesized, with good diastereomeric ratios, un

Ruthenium-Catalyzed Ortho C-H Arylation of Aromatic Nitriles with Arylboronates and Observation of Partial Para Arylation

Ruthenium-catalyzed C-H arylation of aromatic nitriles with arylboronates is described. The use of RuH2(CO){P(4-MeC6H4)3}3 as a catalyst provided higher yields of the ortho arylation products than the