98223-72-4

Basic information

• Product Name: 4-NAPHTHALEN-1-YL-MORPHOLINE
• Synonyms: 4-NAPHTHALEN-1-YL-MORPHOLINE
• CAS NO: 98223-72-4
• Molecular Formula: C14H15NO
• Molecular Weight: 213.27
• Mol File: 98223-72-4.mol
• Article Data: 64

Chemical Properties

• Melting Point: 83 °C
• Boiling Point: 380.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.141±0.06 g/cm3(Predicted)
• PKA: 4.32±0.40(Predicted)
• CAS DataBase Reference: 4-NAPHTHALEN-1-YL-MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NAPHTHALEN-1-YL-MORPHOLINE(98223-72-4)
• EPA Substance Registry System: 4-NAPHTHALEN-1-YL-MORPHOLINE(98223-72-4)

Safety Data

• Hazardous Substances Data: 98223-72-4(Hazardous Substances Data)

Upstream product

• 5765-65-1 4-(benzoyloxy)morpholine 
• 90-14-2 1-Iodonaphthalene 
• 110-91-8 morpholine 
• 74734-13-7 naphthalen-8-yl pivalate 
• 4004-51-7 tri-1-naphthyl phosphate 
• 1351445-39-0 N,N,N-trimethyl-1-naphthalenaminium trifluoromethanesulfonate 
• 99747-74-7 1-naphthyl triflate 
• 13368-42-8 4-(trimethylsilyl)morpholine 
• 36773-67-8 1-naphthoic acid,phenyl ester 
• 580-13-2 2-bromonaphthalene 
• 86-57-7 1-Nitronaphthalene 
• 347370-63-2 C₁₅H₁₅NO₃ 
• 91-20-3 naphthalene 
• 110210-14-5 4-(2,4-dinitrophenoxy)morpholine 

Downstream Products

• 202983-75-3 C₃₁H₃₅N₃O 
• 22871-77-8 5,5-dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane 

Relevant articles and documents

Product selective reaction controlled by the combination of palladium nanoparticles, continuous microwave irradiation, and a co-existing solid; ligand-free Buchwald-Hartwig aminationvs.aryne amination

We have developed a continuous microwave irradiation-assisted Buchwald-Hartwig amination using our original Pd nanoparticle catalyst with a copper plate as a co-existing metal solid. In this methodology, a microwave-controlled product selectivity was achieved between Buchwald-Hartwig amination and aryne amination performed under strongly basic conditions and at a high reaction temperature, because a polar chemical species such as Ar-Pd-halogen might be activated selectively by microwave radiation. Moreover, our catalyst could be used repeatedly over 10 times, and the amount of Pd leaching could be suppressed to a low level.

Nickel-Catalyzed Decarbonylative Amination of Carboxylic Acid Esters

The reaction of carboxylic acid derivatives with amines to form amide bonds has been the most widely used transformation in organic synthesis over the past century. Its utility is driven by the broad availability of the starting materials as well as the kinetic and thermodynamic driving force for amide bond formation. As such, the invention of new reactions between carboxylic acid derivatives and amines that strategically deviate from amide bond formation remains both a challenge and an opportunity for synthetic chemists. This report describes the development of a nickel-catalyzed decarbonylative reaction that couples (hetero)aromatic esters with a broad scope of amines to form (hetero)aryl amine products. The successful realization of this transformation was predicated on strategic design of the cross-coupling partners (phenol esters and silyl amines) to preclude conventional reactivity that forms inert amide byproducts.

Preparation method of pyrazole bistriazolylphosphine compound

The invention discloses a preparation method of a pyrazole bistriazolylphosphine compound. The invention discloses a preparation method of a compound as shown in a formula I. The preparation method comprises the following step: under the action of an alkali, carrying out a phosphonation reaction process as shown in the specification on a compound as shown in a formula II and a compound as shown ina formula III in a solvent in the presence of protective gas to obtain the compound as shown in the formula I, wherein R1 is hydrogen, a C1-C6 alkyl group or a phenyl group, R2 and R3 are phenyl, R4and R5 are independently a C1-C6 alkyl group, a C3-C8 cycloalkyl group or a phenyl group and x is halogen. The pyrazolyl bistriazolylphosphine compound obtained by the preparation method disclosed bythe invention is stable in property, excellent in catalytic effect and high in selectivity, and can be applied to catalytic coupling of amine, boric acid compounds and halides.