22915-82-8

Basic information

• Product Name: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-(4-nitrophenyl)-
• CAS NO: 22915-82-8
• Molecular Formula: C22H12N6O6
• Molecular Weight: 456.374
• Mol File: 22915-82-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-(4-nitrophenyl)-(22915-82-8)
• EPA Substance Registry System: 1,3,4-Oxadiazole, 2,2'-(1,4-phenylene)bis[5-(4-nitrophenyl)-(22915-82-8)

Safety Data

• Hazardous Substances Data: 22915-82-8(Hazardous Substances Data)

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 6926-49-4 5,5'-(1,4-phenylene)bis(1H-tetrazole) 
• 62-23-7 4-nitro-benzoic acid 
• 136-64-1 terephthalohydrazide 
• 623-27-8 terephthalaldehyde, 
• 68-36-0 1,4-bis(trichloromethyl)benzene 
• 636-97-5 N-amino-(4-nitrophenyl)carboxamide 
• 108733-76-2 C₂₂H₁₆N₆O₆ 

Relevant articles and documents

Synthesis and antibacterial activity of some novel bis-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and bis-4-thiazolidinone derivatives from terephthalic dihydrazide

A novel series of 1,4-bis(6-(substituted phenyl)-[1,2,4]-triazolo[3,4-b]-1,3,4-thiadiazoles (5a-b) and 4-bis(substituted phenyl)-4-thiazolidinone derivatives (7a-c) have been synthesized from terephthalic dihydrazide (1) through multistep reaction sequence. 1,4-Bis(5-aryl-1,3,4-oxadiazole-2yl) benzene derivatives (2a-f) and bis-substituted terephthalohydrazide (6a-e) were also synthesized from terephthalic dihydrazide by cyclization with various aromatic acids and aldehydes. Terephthalic dihydrazide (1) was obtained from poly(ethylene terephthalate) waste from reaction with hydrazine hydrate in good yield (86%). All the synthesized compounds were screened for their antibacterial activities against various bacteria and fungi strains. Several of these compounds showed potential antibacterial activity.

An Improved Synthesis of 1,3- and 1,4-Bisbenzenes via Oxidation of Bis-aroylhydrazones of Iso- and Terephthalaldehyde with Lead(IV) Acetate

The oxidation of bis-aroylhydrazones of iso- and terephthalaldehyde with lead(IV) acetate leading to 1,3- and 1,4-bisbenzenes is described.