22996-24-3

Basic information

• Product Name: 4-METHYL-2-NITROBENZYLALCOHOL
• Synonyms: (4-Methyl-2-nitrophenyl)methanol;2-nitro-4-methylbenzyl alcohol
• CAS NO: 22996-24-3
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16
• Mol File: 22996-24-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-METHYL-2-NITROBENZYLALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-2-NITROBENZYLALCOHOL(22996-24-3)
• EPA Substance Registry System: 4-METHYL-2-NITROBENZYLALCOHOL(22996-24-3)

Safety Data

• Hazardous Substances Data: 22996-24-3(Hazardous Substances Data)

Usage

General Description

4-Methyl-2-nitrobenzylalcohol is a chemical compound with the formula C8H9NO3. It is a pale yellow crystalline solid, often used as a reagent in organic synthesis. 4-METHYL-2-NITROBENZYLALCOHOL is used as a protecting group for alcohols and a precursor in the synthesis of various organic compounds. It is also used in the pharmaceutical industry for the production of various medications. 4-Methyl-2-nitrobenzylalcohol has potential applications in the synthesis of advanced materials and as a building block in the development of new drug molecules. It is important to handle this compound with caution as it can be hazardous if not properly handled and stored.

Upstream product

• 20587-29-5 methyl 4-methyl-2-nitrobenzoate 
• 20357-22-6 2-nitro-4-methylbenzaldehyde 
• 27329-27-7 4-methyl-2-nitrobenzoic acid 

Downstream Products

• 1422192-61-7 1-Boc-3-(5-chloro-2-nitrobenzylidene)piperidine 
• 1422192-73-1 1-Boc-3-(5-chloro-2-nitrobenzylidene)piperidine 
• 503856-38-0 diethyl 4-methyl-2-nitrobenzylphosphonate 
• 20357-22-6 2-nitro-4-methylbenzaldehyde 
• 59236-38-3 2-amino-4-methylbenzaldehyde 
• 81335-87-7 (2-amino-4-methylphenyl)methanol 
• 503856-32-4 1-(bromomethyl)-4-methyl-2-nitrobenzene 
• 1290617-55-8 tert-butyl N-(diphenylmethylidene)-4-methyl-2-nitro-L-phenylalaninate 

Relevant articles and documents

MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO

This disclosure relates to compounds having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such compounds and intermediates used in such processes, compositions containing such compounds, and processes of using such compounds against such pests. These compounds/molecules may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. This document discloses compounds having the following formula (Formula One and/or Formula One-A).

Intramolecular Pd-catalyzed reductive amination of enolizable sp3-C-H bonds

A palladium-catalyzed reductive cyclization of nitroarenes has been designed to construct sp3-C-NHAr bonds from sp3-C-H bonds by using an enolizable nucleophile to intercept a nitrosoarene intermediate. Exposure of ortho-substituted nitroarenes to 5 mol ?% of Pd(OAc)2 and 10 mol ?% of phenanthroline under 2 atm of CO constructs partially saturated 5-, 6-, or 7-membered N-heterocycles using α-pyridyl carboxylates, malonates, 1,3-dimethylbarbituric acid, 1,3-diones, or difurans as the nucleophile.

NEW SUBSTITUTED CYANOINDOLINE DERIVATIVES AS NIK INHIBITORS

The present invention relates to pharmaceutical agents of formula (I) useful for therapy and/or prophylaxis in a mammal, and in particular to inhibitors of NF- KB-inducing kinase (NIK - also known as MAP3K14) useful for treating diseases such as cancer, inflammatory disorders, metabolic disorders and autoimmune disorders. The invention is also directed to pharmaceutical compositions comprising such compounds, and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders.